A
Anne Stinn
Researcher at Max Planck Society
Publications - 4
Citations - 124
Anne Stinn is an academic researcher from Max Planck Society. The author has contributed to research in topics: Aryl hydrocarbon receptor & Microscale thermophoresis. The author has an hindex of 2, co-authored 4 publications receiving 55 citations.
Papers
More filters
Journal ArticleDOI
Host Monitoring of Quorum Sensing During Pseudomonas aeruginosa Infection
Pedro Moura-Alves,Pedro Moura-Alves,Andreas Puyskens,Anne Stinn,Marion Klemm,Ute Guhlich-Bornhof,Anca Dorhoi,Anca Dorhoi,Anca Dorhoi,Jens Furkert,Annika Kreuchwig,Jonas Protze,Laura Lozza,Gang Pei,Philippe Saikali,Carolina Perdomo,Hans J. Mollenkopf,Robert Hurwitz,Frank Kirschhoefer,Gerald Brenner-Weiss,January Weiner,Hartmut Oschkinat,Michael Kolbe,Michael Kolbe,Gerd Krause,Stefan H. E. Kaufmann,Stefan H. E. Kaufmann +26 more
TL;DR: The aryl hydrocarbon receptor (AhR) directly recognizes pigmented bacterial virulence factors, such as the phenazines produced by Pseudomonas aeruginosa, which are downstream products of QS, and signals to the host to tune immune responses according to the stage and state of infection.
Journal ArticleDOI
Aryl Hydrocarbon Receptor Modulation by Tuberculosis Drugs Impairs Host Defense and Treatment Outcomes
Andreas Puyskens,Anne Stinn,Michiel van der Vaart,Annika Kreuchwig,Jonas Protze,Gang Pei,Marion Klemm,Ute Guhlich-Bornhof,Robert Hurwitz,Gopinath Krishnamoorthy,Marcel J. M. Schaaf,Gerd Krause,Annemarie H. Meijer,Stefan H. E. Kaufmann,Stefan H. E. Kaufmann,Pedro Moura-Alves,Pedro Moura-Alves +16 more
TL;DR: It is demonstrated that in the context of therapy, the AhR binds several TB drugs, including front line drugs rifampicin and rifabutin, resulting in altered host defense and drug metabolism, and proposed as a potential target for HDT in TB in adjunct to canonical chemotherapy.
Posted ContentDOI
Novel method for quantifying AhR-ligand binding affinities using Microscale Thermophoresis
Anne Stinn,Jens Furkert,Stefan H. E. Kaufmann,Stefan H. E. Kaufmann,Pedro Moura-Alves,Pedro Moura-Alves,Michael Kolbe +6 more
TL;DR: In this article, a microscale thermophoresis-based approach is presented to monitor the binding of purified recombinant human aryl hydrocarbon receptor to its natural ligands in a cell-free system.
Journal ArticleDOI
Novel Method for Quantifying AhR-Ligand Binding Affinities Using Microscale Thermophoresis
Anne Stinn,Jens Furkert,Kaufmann She.,Kaufmann She.,Pedro Moura-Alves,Pedro Moura-Alves,Michael Kolbe +6 more
TL;DR: In this paper, a microscale thermophoresis-based approach is presented to monitor the binding of purified recombinant human aryl hydrocarbon receptor to its natural ligands in a cell-free system.