A
Anu Suomalainen
Researcher at University of Helsinki
Publications - 214
Citations - 19456
Anu Suomalainen is an academic researcher from University of Helsinki. The author has contributed to research in topics: Mitochondrial DNA & Mitochondrial disease. The author has an hindex of 67, co-authored 206 publications receiving 17041 citations. Previous affiliations of Anu Suomalainen include Montreal Neurological Institute and Hospital & University of Eastern Finland.
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Infantile onset spinocerebellar ataxia represents an allelic disease distinct from other hereditary ataxias.
TL;DR: It is reported that the infantile onset spinocerebellar ataxia syndrome does not segregate with any of the markers closely linked to the other hereditary ataxias, Consequently, it represents a genetically distinct disease.
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Phenotypic effects of dietary stress in combination with a respiratory chain bypass in mice.
Praveen K. Dhandapani,Praveen K. Dhandapani,Annina Lyyski,Lars Paulin,Nahid Akhtar Khan,Anu Suomalainen,Petri Auvinen,Eric Dufour,Marten Szibor,Marten Szibor,Howard T. Jacobs,Howard T. Jacobs +11 more
TL;DR: It is concluded that AOX expression in mice does not modify physiological responses to extreme diets, and the microbiome of the most and least obese outliers reared on the ketogenic diet showed no consistent trends compared with animals of normal body weight.
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Cost-effectiveness of whole-exome sequencing in progressive neurological disorders of children.
Juho Aaltio,Virva Hyttinen,Mika Kortelainen,Gerardus W.J. Frederix,Tuula Lönnqvist,Anu Suomalainen,Pirjo Isohanni +6 more
TL;DR: In this article, the diagnostic utility and the cost-effectiveness of whole-exome sequencing (WES) as a routine early-diagnostic tool in children with progressive neurological disorders were clarified.
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Stem cells: Asymmetric rejuvenation.
TL;DR: Organelles called mitochondria are asymmetrically apportioned to the daughters of dividing stem cells according to mitochondrial age, which sheds light on the mechanisms underlying asymmetric stem-cell division.
Journal ArticleDOI
The relevance of mitochondrial DNA variants fluctuation during reprogramming and neuronal differentiation of human iPSCs.
Flavia Palombo,Camille Peron,Leonardo Caporali,Angelo Iannielli,Alessandra Maresca,Ivano Di Meo,Claudio Fiorini,Alice Segnali,Francesca L. Sciacca,Ambra Rizzo,Sonia Levi,Anu Suomalainen,Alessandro Prigione,Vania Broccoli,Valerio Carelli,Valeria Tiranti +15 more
TL;DR: This paper performed mtDNA deep sequencing during the transition from parental fibroblasts to reprogrammed iPSC and differentiated neuronal precursor cells (NPCs) obtained from controls and patients affected by mitochondrial disorders.