A
Anu Suomalainen
Researcher at University of Helsinki
Publications - 214
Citations - 19456
Anu Suomalainen is an academic researcher from University of Helsinki. The author has contributed to research in topics: Mitochondrial DNA & Mitochondrial disease. The author has an hindex of 67, co-authored 206 publications receiving 17041 citations. Previous affiliations of Anu Suomalainen include Montreal Neurological Institute and Hospital & University of Eastern Finland.
Papers
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Characterising metabolically healthy obesity in weight-discordant monozygotic twins
Jussi Naukkarinen,Sini Heinonen,Antti Hakkarainen,J. Lundbom,Katriina Vuolteenaho,Lilli Saarinen,Sampsa Hautaniemi,Amaia Rodríguez,G. Fruehbeck,P. Pajunen,Tuulia Hyötyläinen,Matej Orešič,Eeva Moilanen,Anu Suomalainen,Nina Lundbom,Jaakko Kaprio,Aila Rissanen,Kirsi H. Pietiläinen +17 more
TL;DR: In this paper, the authors aimed to study different fat depots and transcriptional pathways in subcutaneous adipose tissue (SAT) as related to the metabolic healthy obesity (MHO) phenomenon.
Book ChapterDOI
Generation and Characterization of Induced Pluripotent Stem Cells from Patients with mtDNA Mutations.
TL;DR: The iPS technology has now opened up new possibilities for mechanistic studies of disorders with mutations in mitochondrial DNA, a common cause for human disease and often cause very tissue specific phenotypes with vast clinical heterogeneity.
Journal ArticleDOI
Attitudes towards genetic testing and information: does parenthood shape the views?
Antti Saastamoinen,Virva Hyttinen,Mika Kortelainen,Juho Aaltio,Mari Auranen,Emil Ylikallio,Tuula Lönnqvist,Markus T. Sainio,Anu Suomalainen,Henna Tyynismaa,Pirjo Isohanni +10 more
TL;DR: The results suggest that parents are more concerned about their children’s genetic risk factors when compared to the attitudes of adult patients about their own risk.
Impaired mitochondrial biogenesis in adipose tissue in acquired obesity Running title: Impaired mitochondrial function in obesity
Sini Heinonen,Jana Buzkova,Maheswary Muniandy,Risto Kaksonen,Miina Ollikainen,Khadeeja Ismail,Antti Hakkarainen,J. Lundbom,Nina Lundbom,Katriina Vuolteenaho,Eeva Moilanen,Jaakko Kaprio,Aila Rissanen,Anu Suomalainen,Kirsi H. Pietiläinen +14 more
TL;DR: In this paper, the authors examined subcutaneous adipose tissue (SAT) samples from healthy monozygotic twin pairs, aged 22.8 and 36.2 years, who were discordant (∆BMI >3 kg/m 2, mean length of discordance 6.3 ± 0.3 years, n = 26) and concordant for body weight and assessed their detailed mitochondrial metabolic characteristics: mitochondrial-related transcriptomes with dysregulated pathways, mitochondrial DNA (mtDNA) amount, mtDNA-encoded transcripts, and mitochondrial oxidative phosphorylation
Journal ArticleDOI
Mitochondrial DNA Inheritance in Humans: Mix, Match, and Survival of the Fittest.
TL;DR: It is reported that the fate of new mtDNA variants in the female germline is non-random as they report functional selection and matching to nuclear ancestry to shape human mtDNA variation.