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Arleen D. Auerbach
Researcher at Rockefeller University
Publications - 134
Citations - 11167
Arleen D. Auerbach is an academic researcher from Rockefeller University. The author has contributed to research in topics: Fanconi anemia & FANCA. The author has an hindex of 50, co-authored 131 publications receiving 10551 citations. Previous affiliations of Arleen D. Auerbach include Icahn School of Medicine at Mount Sinai & Medical College of Wisconsin.
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Journal ArticleDOI
A 20-year perspective on the International Fanconi Anemia Registry (IFAR)
David I. Kutler,Bhuvanesh Singh,Bhuvanesh Singh,Bhuvanesh Singh,Jaya M. Satagopan,Jaya M. Satagopan,Jaya M. Satagopan,Sat Dev Batish,Sat Dev Batish,Sat Dev Batish,Marianne Berwick,Marianne Berwick,Marianne Berwick,Philip F. Giampietro,Philip F. Giampietro,Philip F. Giampietro,Helmut Hanenberg,Helmut Hanenberg,Helmut Hanenberg,Arleen D. Auerbach +19 more
TL;DR: The results of this study of patients registered in the IFAR over a 20-year period provide information that will enable better prediction of outcome and aid clinicians with decisions regarding major therapeutic modalities.
Journal ArticleDOI
A note on competing risks in survival data analysis
Jaya M. Satagopan,Leah Ben-Porat,Marianne Berwick,Mark E. Robson,David I. Kutler,Arleen D. Auerbach +5 more
TL;DR: Two published data sets are illustrated and the resulting estimates are compared with those obtained using the Kaplan–Meier approach to demonstrate the importance of appropriately estimating the cumulative incidence of an event of interest in the presence of competing risk events.
Journal ArticleDOI
Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer
Sarah Reid,Detlev Schindler,Helmut Hanenberg,Helmut Hanenberg,Karen Barker,Sandra Hanks,Reinhard Kalb,Kornelia Neveling,Patrick Kelly,Sheila Seal,Marcel Freund,Melanie Wurm,Sat Dev Batish,Sat Dev Batish,Francis P. Lach,Sevgi Yetgin,Heidemarie Neitzel,Hany Ariffin,Marc Tischkowitz,Marc Tischkowitz,Christopher G. Mathew,Arleen D. Auerbach,Nazneen Rahman +22 more
TL;DR: It is demonstrated that biallelic PALB2 mutations cause a new subtype of Fanconi anemia, FA-N, and, similar to bIALlelic BRCA2 mutations, confer a high risk of childhood cancer.
Journal ArticleDOI
Fanconi anemia and its diagnosis
TL;DR: This overview will present the current knowledge regarding the varied phenotypic manifestations of FA and procedures for diagnosis based upon abnormal DNA damage responses and diagnosis based on abnormal response to DNA crosslinking agents.
Journal ArticleDOI
The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia.
Orna Levran,Claire L. Attwooll,Rashida Henry,Kelly Milton,Kornelia Neveling,Paula Río,Sat Dev Batish,Reinhard Kalb,Eunike Velleuer,Sandra Barral,Jurg Ott,John H.J. Petrini,Detlev Schindler,Helmut Hanenberg,Arleen D. Auerbach +14 more
TL;DR: Using genetic mapping, mutation identification and western-blot data, it is identified the defective protein in FA-J cells as BRIP1, a DNA helicase that is a binding partner of the breast cancer tumor suppressor BRCA1.