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Arnau Sebé-Pedrós
Researcher at Pompeu Fabra University
Publications - 53
Citations - 3367
Arnau Sebé-Pedrós is an academic researcher from Pompeu Fabra University. The author has contributed to research in topics: Multicellular organism & Gene. The author has an hindex of 24, co-authored 48 publications receiving 2433 citations. Previous affiliations of Arnau Sebé-Pedrós include Weizmann Institute of Science & Spanish National Research Council.
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Journal ArticleDOI
The Capsaspora genome reveals a complex unicellular prehistory of animals
Hiroshi Suga,Zehua Chen,Alex de Mendoza,Arnau Sebé-Pedrós,Matthew Brown,Eric Kramer,Martin Carr,Pierre Kerner,Michel Vervoort,Núria Sánchez-Pons,Guifré Torruella,Romain Derelle,Gerard Manning,B. Franz Lang,Carsten Russ,Brian J. Haas,Andrew J. Roger,Chad Nusbaum,Iñaki Ruiz-Trillo,Iñaki Ruiz-Trillo,Iñaki Ruiz-Trillo +20 more
TL;DR: It is proposed that the acquisition of these metazoan-specific developmental systems and the co-option of pre-existing genes drove the evolutionary transition from unicellular protists to metazoans.
Journal ArticleDOI
Cnidarian Cell Type Diversity and Regulation Revealed by Whole-Organism Single-Cell RNA-Seq
Arnau Sebé-Pedrós,Baptiste Saudemont,Baptiste Saudemont,Elad Chomsky,Flora Plessier,Flora Plessier,Flora Plessier,Marie-Pierre Mailhé,Marie-Pierre Mailhé,Justine Renno,Justine Renno,Yann Loe-Mie,Yann Loe-Mie,Aviezer Lifshitz,Zohar Mukamel,Sandrine Schmutz,Sophie Novault,Patrick R. H. Steinmetz,François Spitz,François Spitz,Amos Tanay,Heather Marlow,Heather Marlow +22 more
TL;DR: This study performs whole-organism single-cell transcriptomics to map adult and larval cell types in the cnidarian Nematostella vectensis, a non-bilaterian animal with complex tissue-level body-plan organization and identifies the regulatory codes that underlie Nem atostella cell-specific expression.
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Ancient origin of the integrin-mediated adhesion and signaling machinery
TL;DR: A comparative genomic analysis of the integrin adhesion machinery is reported, finding that core components are encoded in the genome of the apusozoan protist Amastigomonas sp.
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The origin of Metazoa: a unicellular perspective
TL;DR: Results of these investigations into the identification and characterization of the genomic and cellular traits of the protists most closely related to animals are reviewed and their implications for understanding the earliest stages of animal evolution are discussed.
Journal ArticleDOI
Early metazoan cell type diversity and the evolution of multicellular gene regulation
Arnau Sebé-Pedrós,Elad Chomsky,Kevin Pang,David Lara-Astiaso,Federico Gaiti,Zohar Mukamel,Ido Amit,Andreas Hejnol,Bernard M. Degnan,Amos Tanay +9 more
TL;DR: It is demonstrated that metazoan cell types can be defined by networks of transcription factors and proximal promoters, and indicate that further genome regulatory complexity may be required for more diverse cell type repertoires.