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Arthur C. Ouwehand
Researcher at DuPont
Publications - 322
Citations - 23844
Arthur C. Ouwehand is an academic researcher from DuPont. The author has contributed to research in topics: Probiotic & Bifidobacterium. The author has an hindex of 80, co-authored 309 publications receiving 21180 citations. Previous affiliations of Arthur C. Ouwehand include University of Gothenburg & Danisco.
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Journal ArticleDOI
The Effects of Polydextrose and Xylitol on Microbial Community and Activity in a 4-Stage Colon Simulator
TL;DR: In vitro studies provide evidence to the prebiotic characteristics of polydextrose and xylitol and demonstrate a beneficial shift in the metabolic patterns of the colon microbes was measured with both of the tested products.
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Safety assessment of Lactobacillus strains: presence of putative risk factors in faecal, blood and probiotic isolates.
Satu Vesterlund,Vanessa Vankerckhoven,Maija Saxelin,Herman Goossens,Herman Goossens,Seppo Salminen,Arthur C. Ouwehand +6 more
TL;DR: None of the measurable virulence factors were found to be present at statistically higher level in clinical blood isolates when compared to faecal and/or probiotic isolates indicating that these factors do not cause risk when safety of probiotics is considered.
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Probiotic use in at-risk populations
Mary E. Sanders,Daniel Merenstein,Arthur C. Ouwehand,Gregor Reid,Seppo Salminen,Michael D. Cabana,George Paraskevakos,Gregory Leyer +7 more
TL;DR: It is in patients' best interest to use probiotics in the prevention and treatment of conditions when the evidence is convincing and to protect high-risk patients, probiotic products should meet stringent microbiological standards.
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Irritable bowel syndrome symptom severity improves equally with probiotic and placebo
Anna Lyra,Markku Hillilä,Teppo Huttunen,Sofia Männikkö,Mikko Taalikka,Julia Tennilä,Anneli Tarpila,Sampo J. Lahtinen,Arthur C. Ouwehand,Lea Veijola +9 more
TL;DR: NCFM alleviates moderate to severe abdominal pain, consistent with earlier observations of this strain mitigating visceral pain through increased analgesic receptor expression.
Journal ArticleDOI
Effects of genetic, processing, or product formulation changes on efficacy and safety of probiotics
Mary Ellen Sanders,Todd R. Klaenhammer,Arthur C. Ouwehand,Bruno Pot,Eric Johansen,James T. Heimbach,Maria L. Marco,Julia Tennilä,R. Paul Ross,Charles M. A. P. Franz,Nicolas Page,R. David Pridmore,Greg Leyer,Seppo Salminen,Duane Larry Charbonneau,Emma K. Call,Irene Lenoir-Wijnkoop +16 more
TL;DR: This review explores whether genetic or phenotypic changes, by accident or design, might affect the efficacy or safety of commercial probiotics, and highlights key issues important to determining the need to re‐confirm efficacy orSafety after strain improvement, process optimization, or product formulation changes.