A
Arthur M. Feldman
Researcher at Thomas Jefferson University
Publications - 296
Citations - 41891
Arthur M. Feldman is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Heart failure & Tumor necrosis factor alpha. The author has an hindex of 79, co-authored 289 publications receiving 40355 citations. Previous affiliations of Arthur M. Feldman include Johns Hopkins University School of Medicine & Valley Hospital.
Papers
More filters
Journal ArticleDOI
Diminished beta-adrenergic receptor responsiveness and cardiac dilation in hearts of myopathic Syrian hamsters (BIO 53.58) are associated with a functional abnormality of the G stimulatory protein.
Arthur M. Feldman,R G Tena,Paul D. Kessler,Harlan F. Weisman,Steven P. Schulman,Roger S. Blumenthal,D. G. Jackson,C Van Dop +7 more
TL;DR: G protein changes are associated with ventricular dilation in BIO 53.58 hamsters and that G protein levels are not always reflective of G protein bioactivity.
Journal ArticleDOI
Chronic exposure to interleukin 1beta induces a delayed and reversible alteration in excitation-contraction coupling of cultured cardiomyocytes.
Alain Combes,Carole S. Frye,Bonnie Lemster,Steven S. Brooks,Simon C. Watkins,Arthur M. Feldman,Charles F. McTiernan +6 more
TL;DR: The hypothesis that IL-1β may play an important role in contractile dysfunction through alterations in calcium homeostasis is supported.
Journal ArticleDOI
Phospholamban gene ablation improves calcium transients but not cardiac function in a heart failure model.
Andrzej M. Janczewski,Maliha Zahid,Bonnie Lemster,Carol S. Frye,Gregory A. Gibson,Yoshihiro Higuchi,Evangelia G. Kranias,Arthur M. Feldman,Charles F. McTiernan +8 more
TL;DR: In this article, the authors showed that PLB ablation did not improve survival, cardiac function, or limit cardiac chamber dilation and hypertrophy in TNF1.6 mice.
Journal ArticleDOI
The beta-adrenergic pathway in the failing human heart: implications for inotropic therapy.
Journal ArticleDOI
Matrix metalloproteinases in the progression of heart failure: Potential therapeutic implications
Yun You Li,Arthur M. Feldman +1 more
TL;DR: Results suggest that modulation of MMP activity can prevent myocardial dysfunction and the progression of heart failure through alterations in the remodelling process of extracellular matrix and the left ventricle.