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Arthur M. Feldman
Researcher at Thomas Jefferson University
Publications - 296
Citations - 41891
Arthur M. Feldman is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Heart failure & Tumor necrosis factor alpha. The author has an hindex of 79, co-authored 289 publications receiving 40355 citations. Previous affiliations of Arthur M. Feldman include Johns Hopkins University School of Medicine & Valley Hospital.
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Journal ArticleDOI
The role of tumor necrosis factor in the pathophysiology of heart failure.
Arthur M. Feldman,Alain Combes,Daniel R. Wagner,Toshiaki Kadakomi,Toru Kubota,Yun You Li,Charles F. McTiernan +6 more
TL;DR: The biology of T NF, its role in inflammatory diseases, the effects of TNF on the physiology of the heart and the development of clinical strategies that target the cytokine pathways are reviewed.
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Effects of vesnarinone on morbidity and mortality in patients with heart failure
Arthur M. Feldman,Michael R. Bristow,William W. Parmley,Peter E. Carson,Carl J. Pepine,Edward M. Gilbert,John E. Strobeck,Grady H. Hendrix,Eric R. Powers,Raymond P. Bain,Bill G. White +10 more
TL;DR: Six months of therapy with 60 mg of vesnarinone per day resulted in lower morbidity and mortality and improved the quality of life of patients with congestive heart failure, however, a higher dose of veNarinone (120 mg per day) increased mortality, suggesting that this drug has a narrow therapeutic range.
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ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult—Summary Article
Sharon A. Hunt,William T. Abraham,Marshall H. Chin,Arthur M. Feldman,Gary S. Francis,Theodore G. Ganiats,Mariell Jessup,Marvin A. Konstam,Donna Mancini,Keith Michl,John A. Oates,Peter S. Rahko,Marc A. Silver,Lynne W. Stevenson,Clyde W. Yancy,Elliott M. Antman,Sidney C. Smith,Cynthia D. Adams,Jeffrey L. Anderson,David P. Faxon,Valentin Fuster,Jonathan L. Halperin,Loren F. Hiratzka,Alice K. Jacobs,Rick A. Nishimura,Joseph P. Ornato,Richard L. Page,Barbara Riegel +27 more
TL;DR: The American College of Cardiology (ACC)/AHA Task Force on Practice Guidelines regularly reviews existing guidelines to determine when an update or full revision is needed.
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Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases and their regulators in cardiac matrix remodeling.
TL;DR: It is suggested that the interplay of MMPs and their regulators is important in the development of the heart failure phenotype, and myocardial fibrosis in heart failure may be modified by modulating MMP activity.
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Sudden cardiac death in heart failure. The role of abnormal repolarization.
Gordon F. Tomaselli,Dirk J. Beuckelmann,Hugh Calkins,Ronald D. Berger,Paul D. Kessler,John H. Lawrence,David A. Kass,Arthur M. Feldman,Eduardo Marbán +8 more
TL;DR: Evidence is examined for the hypothesis that alteration of repolarizing K+ channel expression in failing myocardium predisposes to abnormalities inRepolarization that are arrhythmogenic, and the possible utility of novel electrophysiological and ECG measures of altered ventricular repolarization will be explored.