A
Arthur M. Feldman
Researcher at Thomas Jefferson University
Publications - 296
Citations - 41891
Arthur M. Feldman is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Heart failure & Tumor necrosis factor alpha. The author has an hindex of 79, co-authored 289 publications receiving 40355 citations. Previous affiliations of Arthur M. Feldman include Johns Hopkins University School of Medicine & Valley Hospital.
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Journal ArticleDOI
Cardioprotection afforded by NF-κB ablation is associated with activation of Akt in mice overexpressing TNF-α
Yoshihiro Higuchi,Tung O. Chan,Maria Brown,Jin Zhang,Brent R. DeGeorge,Hajime Funakoshi,Gregory A. Gibson,Charles F. McTiernan,Toru Kubota,W. Keith Jones,Arthur M. Feldman +10 more
TL;DR: When selectively overexpressed in mouse heart, TNF-α effects the development of a cardiomyopathy that closely mimics that seen in human failing hearts.
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Overexpression of tumor necrosis factor-α increases production of hydroxyl radical in murine myocardium
Yoji Machida,Toru Kubota,Natsumi Kawamura,Hajime Funakoshi,Tomomi Ide,Hideo Utsumi,Yun You Li,Arthur M. Feldman,Hiroyuki Tsutsui,Hiroaki Shimokawa,Akira Takeshita +10 more
TL;DR: Although cyclophosphamide significantly suppressed the infiltration of inflammatory cells, it did not diminish the production of hydroxyl radical in TG myocardium, indicating that damaged myocytes, but not infiltratinginflammatory cells, may be the source of ROS in TG.
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Mechanical cardiac support 2000: current applications and future trial design: June 15–16, 2000 Bethesda, Maryland
Lynne W. Stevenson,Robert L. Kormos,Mark L. Barr,Maria Rosa Costanzo,Patrice Desvigne-Nickens,Arthur M. Feldman,O. Howard Frazier,Lawrence S. Friedman,J. Donald Hill,Marvin A. Konstam,Patrick M. McCarthy,Robert E. Michler,Mehmet C. Oz,Bruce R. Rosengard,Wolf Sapirstein,Rhona Shanker,Craig R. Smith,Randall C. Starling,David O. Taylor,Alison Wichman +19 more
TL;DR: This research was supported by a grant from the National Science Foundation and the US Department of Energy's Office of Science and Technology Policy.
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Left ventricular dysfunction in murine models of heart failure and in failing human heart is associated with a selective decrease in the expression of caveolin-3.
Ellina Cheskis Feiner,Paul J. Chung,Jean-Francois Jasmin,Jin Zhang,Diana Whitaker-Menezes,Valerie Myers,Jianliang Song,Elizabeth W. Feldman,Hajime Funakoshi,Brent R. DeGeorge,R. V. Yelamarty,Walter J. Koch,Michael P. Lisanti,Charles F. McTiernan,Joseph Y. Cheung,Michael R. Bristow,Tung O. Chan,Arthur M. Feldman +17 more
TL;DR: A relationship between left ventricular dysfunction and caveolin-3 levels is suggested and it is suggested that caveolini-3 may provide a novel target for heart failure therapy.
Journal ArticleDOI
Enhanced external counterpulsation in the management of patients with cardiovascular disease
TL;DR: Ongoing clinical trials in patients with significant left ventricular dysfunction, an international registry, and additional clinical trials may help to elucidate further the role of this novel and unique therapy in the clinical armamentarium.