A
Atsuko Shigenari
Researcher at Tokai University
Publications - 43
Citations - 973
Atsuko Shigenari is an academic researcher from Tokai University. The author has contributed to research in topics: Human leukocyte antigen & Haplotype. The author has an hindex of 15, co-authored 40 publications receiving 894 citations.
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Journal ArticleDOI
Super high resolution for single molecule‐sequence‐based typing of classical HLA loci at the 8‐digit level using next generation sequencers
Takashi Shiina,Shingo Suzuki,Yuki Ozaki,H Taira,Eri Kikkawa,Atsuko Shigenari,Akira Oka,Takeji Umemura,Satoru Joshita,O Takahashi,Y Hayashi,M Paumen,Yoshihiko Katsuyama,Shigeki Mitsunaga,Masao Ota,Jerzy K. Kulski,Hidetoshi Inoko +16 more
TL;DR: The SS-SBT method described here is a superior and effective HLA DNA typing method to efficiently detect new HLA alleles and null alleles without ambiguity.
Journal ArticleDOI
The genomic sequence and analysis of the swine major histocompatibility complex
Christine Renard,E. Hart,Harminder Sehra,Helen Beasley,Penny Coggill,Kerstin Howe,Jen Harrow,James G. R. Gilbert,Sarah Sims,Jane Rogers,Asako Ando,Atsuko Shigenari,Takashi Shiina,Hidetoshi Inoko,Patrick Chardon,Stephan Beck +15 more
TL;DR: The generation and analysis of an integrated sequence map of a 2.4-Mb region of pig chromosome 7, comprising the classical class I region, the extended and classical class II regions, and the class III region of the major histocompatibility complex (MHC), also known as swine leukocyte antigen (SLA) complex is described.
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Comparative sequencing of human and chimpanzee MHC class I regions unveils insertions/deletions as the major path to genomic divergence
Tatsuya Anzai,Takashi Shiina,Natsuki Kimura,Kazuyo Yanagiya,Sakae Kohara,Atsuko Shigenari,Tetsushi Yamagata,Jerzy K. Kulski,Taeko K. Naruse,Yoshifumi Fujimori,Yasuhito Fukuzumi,Masaaki Yamazaki,Hiroyuki Tashiro,Chie Iwamoto,Yumi Umehara,Tadashi Imanishi,Alice Meyer,Kazuho Ikeo,Takashi Gojobori,Seiamak Bahram,Hidetoshi Inoko +20 more
TL;DR: A large-scale single-contig comparison between human and chimpanzee genomes via the sequence analysis of almost one-half of the immunologically critical MHC was performed in this article.
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Genetic polymorphism of the swine major histocompatibility complex ( SLA ) class I genes, SLA-1 , -2 and -3
Asako Ando,H. Kawata,Atsuko Shigenari,Tatsuya Anzai,Masao Ota,Yoshihiko Katsuyama,Masaharu Sada,Rieko Goto,Shin-nosuke Takeshima,Yoko Aida,Takahiro Iwanaga,Nobuyuki Fujimura,Yoshiyuki Suzuki,Takashi Gojobori,Hidetoshi Inoko +14 more
TL;DR: The results suggest that selective forces operating in the SLA class I molecules are almost similar to those of the HLA class–I molecules, although several functional sites for antigen and cytotoxic T-lymphocyte recognition by theSLA class-I molecules may be different from those ofThe HLAclass I molecule.
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Rapid assignment of the swine major histocompatibility complex (SLA) class I and II genotypes in Clawn miniature swine using PCR-SSP and PCR-RFLP methods.
Asako Ando,Masao Ota,Masaharu Sada,Yoshihiko Katsuyama,Rieko Goto,Atsuko Shigenari,H. Kawata,Tatsuya Anzai,Takahiro Iwanaga,Yukari Miyoshi,Nobuyuki Fujimura,Hidetoshi Inoko +11 more
TL;DR: Inbred miniature swine with defined novel SLA haplotypes will be useful in allo‐ and xeno‐transplantation studies, which can be carried out representing variable combinations of SLAhaplotypes.