J
Jen Harrow
Researcher at Wellcome Trust Sanger Institute
Publications - 16
Citations - 711
Jen Harrow is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Gene & Elixir (programming language). The author has an hindex of 8, co-authored 16 publications receiving 651 citations.
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Journal ArticleDOI
Comparative analysis of the transcriptome across distant species
Mark Gerstein,Joel Rozowsky,Koon-Kiu Yan,Daifeng Wang,Chao Cheng,James B. Brown,James B. Brown,Carrie A. Davis,LaDeana W. Hillier,Cristina Sisu,Jingyi Jessica Li,Jingyi Jessica Li,Baikang Pei,Arif Harmanci,Michael O. Duff,Sarah Djebali,Roger P. Alexander,Burak H. Alver,Raymond K. Auerbach,Kimberly Bell,Peter J. Bickel,Max E. Boeck,Nathan Boley,Nathan Boley,Benjamin W. Booth,Lucy Cherbas,Peter Cherbas,Chao Di,Alexander Dobin,Jorg Drenkow,Brent Ewing,Gang Fang,Megan Fastuca,Elise A. Feingold,Adam Frankish,Guanjun Gao,Peter J. Good,Roderic Guigó,Ann S. Hammonds,Jen Harrow,Roger A. Hoskins,Cédric Howald,Cédric Howald,Long Hu,Haiyan Huang,Tim Hubbard,Tim Hubbard,Chau Huynh,Sonali Jha,Dionna M. Kasper,Masaomi Kato,Thomas C. Kaufman,Robert R. Kitchen,Erik Ladewig,Julien Lagarde,Eric C. Lai,Jing Leng,Zhi Lu,Michael J. MacCoss,Gemma E. May,Gemma E. May,Rebecca McWhirter,Gennifer E. Merrihew,David M. Miller,Ali Mortazavi,Rabi Murad,Brian Oliver,Sara Olson,Peter J. Park,Michael J. Pazin,Norbert Perrimon,Norbert Perrimon,Dmitri D. Pervouchine,Valerie Reinke,Alexandre Reymond,Garrett Robinson,Anastasia Samsonova,Anastasia Samsonova,Gary Saunders,Gary Saunders,Felix Schlesinger,Anurag Sethi,Frank J. Slack,William C. Spencer,Marcus H. Stoiber,Marcus H. Stoiber,Pnina Strasbourger,Andrea Tanzer,Andrea Tanzer,Owen Thompson,Kenneth H. Wan,Guilin Wang,Huaien Wang,Kathie L. Watkins,Jiayu Wen,Kejia Wen,Chenghai Xue,Li Yang,Li Yang,Kevin Y. Yip,Chris Zaleski,Yan Zhang,Henry Zheng,Steven E. Brenner,Brenton R. Graveley,Susan E. Celniker,Thomas R. Gingeras,Robert H. Waterston +107 more
TL;DR: It is found in all three organisms that the gene-expression levels, both coding and non-coding, can be quantitatively predicted from chromatin features at the promoter using a ‘universal model’ based on a single set of organism-independent parameters.
Journal ArticleDOI
The genomic sequence and analysis of the swine major histocompatibility complex
Christine Renard,E. Hart,Harminder Sehra,Helen Beasley,Penny Coggill,Kerstin Howe,Jen Harrow,James G. R. Gilbert,Sarah Sims,Jane Rogers,Asako Ando,Atsuko Shigenari,Takashi Shiina,Hidetoshi Inoko,Patrick Chardon,Stephan Beck +15 more
TL;DR: The generation and analysis of an integrated sequence map of a 2.4-Mb region of pig chromosome 7, comprising the classical class I region, the extended and classical class II regions, and the class III region of the major histocompatibility complex (MHC), also known as swine leukocyte antigen (SLA) complex is described.
Journal ArticleDOI
The pig X and Y Chromosomes: structure, sequence, and evolution
Benjamin M. Skinner,Carole A. Sargent,Carol Churcher,Toby Hunt,Javier Herrero,Javier Herrero,Jane E. Loveland,Matthew Dunn,Sandra Louzada,Beiyuan Fu,William Chow,James G. R. Gilbert,Siobhan Austin-Guest,Kathryn Beal,Denise Carvalho-Silva,William Cheng,Daria Gordon,Darren Grafham,Matthew Hardy,Jo Harley,Heidi Hauser,Philip Howden,Philip Howden,Kerstin Howe,Kim Lachani,Peter J.I. Ellis,Daniel Kelly,Giselle Kerry,James Kerwin,Bee Ling Ng,Glen Threadgold,Thomas Wileman,Jonathan Wood,Fengtang Yang,Jen Harrow,Nabeel A. Affara,Chris Tyler-Smith +36 more
TL;DR: This sequencing project has allowed us to identify genes--both single copy and amplified--on the pig Y chromosome, to compare the pig X and Y Chromosomes for homologous sequences, and thereby to reveal mechanisms underlying pig X/Y Chromosome evolution.
Journal ArticleDOI
RNAcentral: A vision for an international database of RNA sequences
Alex Bateman,Shipra Agrawal,Ewan Birney,Elspeth A. Bruford,Janusz M. Bujnicki,Janusz M. Bujnicki,Guy Cochrane,James R. Cole,Marcel E. Dinger,Anton J. Enright,Paul P. Gardner,Daniel Gautheret,Sam Griffiths-Jones,Jen Harrow,Javier Herrero,Ian Holmes,Hsien D A Huang,Krystyna A. Kelly,Paul J. Kersey,Ana Kozomara,Todd M. Lowe,Manja Marz,Simon Moxon,Kim D. Pruitt,Tore Samuelsson,Peter F. Stadler,Albert J. Vilella,Jan Hinnerk Vogel,Kelly P. Williams,Mathew W. Wright,Christian W Zwieb +30 more
TL;DR: This article proposes the creation of a new open public resource that is term RNAcentral, which will contain a comprehensive collection of RNA sequences and fill an important gap in the provision of biomedical databases.
Journal ArticleDOI
The GENCODE exome: sequencing the complete human exome
Alison J. Coffey,Felix Kokocinski,Maria S Calafato,Carol Scott,Priit Palta,Priit Palta,Priit Palta,Eleanor Drury,Christopher J. Joyce,Emily M LeProust,Jen Harrow,Sarah E. Hunt,Anna-Elina Lehesjoki,Daniel J. Turner,Tim Hubbard,Aarno Palotie +15 more
TL;DR: The design of an extended set of targets for capturing the complete human exome, based on annotation from the GENCODE consortium, is reported, which covers an additional 5594 genes and 10.3 Mb compared with the current CCDS-based sets.