Aurora Piazza

TL;DR: The results of the Oltrepò Pavese water compartment antibiotic-resistance contamination rates highlight the need to improve hygienic measures to reduce the load of discharged bacteria with emerging resistance mechanisms.

TL;DR: The identification and characterization of a novel resistance mechanism to BTZ in Mycobacterium smegmatis is described and the crystal structure of NfnB in complex with the essential cofactor flavin mononucleotide is reported, and it is shown that a common amino acid stretch between N fnB and DprE1 is likely to be essential for the interaction with BTZ.

TL;DR: OXA-23 enzymes have become the most prevalent carbapenemases and are now endemic in Italy, and molecular typing profiles showed the presence of international and national clonal lineages in Italy.

TL;DR: The results suggest that in M. smegmatis only IdeR-dependent regulation is retained, while zinc has no effect on gene expression, and cluster 3 induction in acid stress conditions strengthens the hypothesis that cluster 3 is expressed in the course of infection.

TL;DR: Comparing the most frequently used Klebsiella pneumoniae typing methods showed that cgMLST and coreSNP are more discriminant than PFGE, and that both approaches are suitable for transmission analyses, and highlights the limits of cg MLST scheme genes for phylogenetic reconstructions.