A
Avraham Eisbruch
Researcher at University of Michigan
Publications - 294
Citations - 22057
Avraham Eisbruch is an academic researcher from University of Michigan. The author has contributed to research in topics: Head and neck cancer & Radiation therapy. The author has an hindex of 72, co-authored 284 publications receiving 19700 citations.
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Journal ArticleDOI
Use of normal tissue complication probability models in the clinic.
Lawrence B. Marks,Ellen Yorke,Andrew Jackson,Randall K. Ten Haken,Louis S. Constine,Avraham Eisbruch,Søren M. Bentzen,Jiho Nam,Joseph O. Deasy +8 more
TL;DR: The Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) review summarizes the currently available three-dimensional dose/volume/outcome data to update and refine the normal tissue dose/ volume tolerance guidelines provided by the classic Emami et al. paper published in 1991.
Journal ArticleDOI
Dose, volume, and function relationships in parotid salivary glands following conformal and intensity-modulated irradiation of head and neck cancer
TL;DR: Dose/volume/function relationships in the parotid glands are characterized by dose and volume thresholds, steep dose/response relationships when the thresholds are reached, and a maximal volume dependence parameter in the NTCP model.
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Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial
Maura L. Gillison,Andy Trotti,Jonathan Harris,Avraham Eisbruch,Paul M. Harari,David J. Adelstein,Richard C.K. Jordan,Weiqiang Zhao,Erich M. Sturgis,Barbara Burtness,John A. Ridge,Jolie Ringash,James M. Galvin,Min Yao,Shlomo A. Koyfman,Dukagjin Blakaj,Mohammed A. Razaq,A. Dimitrios Colevas,Jonathan J. Beitler,Christopher U. Jones,Neal Dunlap,Samantha A. Seaward,Sharon A. Spencer,Thomas J. Galloway,Jack Phan,James J. Dignam,James J. Dignam,Quynh-Thu Le +27 more
TL;DR: After median follow-up duration of 4·5 years, radiotherapy plus cetuximab did not meet the non-inferiority criteria for overall survival, and patients were stratified by T category (T1-T2 vs T3-T4), N category (N0-N2a vs N2b-N3), Zubrod performance status (0 vs 1), and tobacco smoking history (≤10 pack-years).
Journal ArticleDOI
Xerostomia and its predictors following parotid-sparing irradiation of head-and-neck cancer
Avraham Eisbruch,Hyungjin Myra Kim,Jeffrey E. Terrell,Jeffrey E. Terrell,Lon H. Marsh,Laura A. Dawson,Jonathan A. Ship +6 more
TL;DR: An improvement over time in xerostomia, occurring in tandem with rising salivary production from the spared major Salivary glands, suggests a long-term clinical benefit from their sparing.
Journal ArticleDOI
CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC,RTOG consensus guidelines.
Vincent Grégoire,Peter C. Levendag,Kian K. Ang,Jacques Bernier,Marijel Braaksma,Volker Budach,Cliff Chao,Emmanuel Coche,Jay S. Cooper,Guy Cosnard,Avraham Eisbruch,Samy El-Sayed,Bahman Emami,Cai Grau,Marc Hamoir,Nancy Y. Lee,Philippe Maingon,Karin Muller,Hervé Reychler +18 more
TL;DR: The objective of the present article is to present the consensus guidelines for the delineation of the node levels in the node-negative neck, and representative CTVs that are consistent with these guidelines are illustrated on CT sections.