J
Jacques Bernier
Researcher at University of Geneva
Publications - 9
Citations - 1902
Jacques Bernier is an academic researcher from University of Geneva. The author has contributed to research in topics: Radiosensitivity & DAHANCA. The author has an hindex of 6, co-authored 9 publications receiving 1797 citations. Previous affiliations of Jacques Bernier include University of Milan & European Organisation for Research and Treatment of Cancer.
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Journal ArticleDOI
Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis
Jean Bourhis,Jens Overgaard,Hélène Audry,Kian K. Ang,M.I. Saunders,Jacques Bernier,Jean-Claude Horiot,Aurélie Le Maître,Thomas F. Pajak,Michael Poulsen,Brian O'Sullivan,W. Dobrowsky,Andrzej Hliniak,Krzysztof Składowski,John Hay,Luiz H. J. Pinto,Carlo Fallai,Karen K. Fu,Richard Sylvester,Jean-Pierre Pignon +19 more
TL;DR: Comparison of the different types of altered radiotherapy suggests that hyperfractionation has the greatest benefit, whereas the benefit on nodal control was less pronounced.
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CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC,RTOG consensus guidelines.
Vincent Grégoire,Peter C. Levendag,Kian K. Ang,Jacques Bernier,Marijel Braaksma,Volker Budach,Cliff Chao,Emmanuel Coche,Jay S. Cooper,Guy Cosnard,Avraham Eisbruch,Samy El-Sayed,Bahman Emami,Cai Grau,Marc Hamoir,Nancy Y. Lee,Philippe Maingon,Karin Muller,Hervé Reychler +18 more
TL;DR: The objective of the present article is to present the consensus guidelines for the delineation of the node levels in the node-negative neck, and representative CTVs that are consistent with these guidelines are illustrated on CT sections.
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Exploitable mechanisms for combining drugs with radiation: concepts, achievements and future directions.
TL;DR: Spatial cooperation, cytotoxic enhancement, biological cooperation, temporal modulation and normal tissue protection are proposed as five primary exploitable mechanisms for the rational combination of drugs with radiation for cancer therapy.
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Comparative dosimetric evaluation of the simultaneous integrated boost with photon intensity modulation in head and neck cancer patients.
TL;DR: Feasibility of SIB techniques and in particular of the modified SIB appears to be dosimetrically proven and the results reported here justify the activation of a phase I protocol to verify clinically their impact using IMRT photon-based techniques.
Journal ArticleDOI
Transfer of Ku86 RNA antisense decreases the radioresistance of human fibroblasts.
Elisabetta Marangoni,Muriel Le Romancer,Nicolas Foray,Catherine Muller,Sétha Douc-Rasy,Sabine Vaganay,Bassam Abdulkarim,Michel Barrois,Patrick Calsou,Jacques Bernier,Bernard Salles,Jean Bourhis +11 more
TL;DR: This study is the first to show the implication of Ku86 in DSB repair and in the radiosensitivity of human cells and strongly suggests that Ku86 could constitute an appealing target for combining gene therapy and radiation therapy.