B. de Kruijff

TL;DR: The relationship between protein-induced bilayer permeability and lipid transbilayer movement in both vesicle preparations is discussed and the role of protein aggregation and the formation of defects in the lipid bilayer on membrane permeability

TL;DR: An analysis of the pH and delta pH dependencies of the process demonstrated that the K+ diffusion potential-induced peptide accumulation is largely determined by a redistribution of peptide according to the transbilayer pH gradient, in agreement with a translocation across the vesicle membrane of the neutral, deprotonated form of the peptide.

TL;DR: The interaction between beta-lactoglobulin and sonicated aqueous dispersions of the gel phase forming monoglyceride monostearoylglycerol were studied using isothermal titration calorimetry, direct binding experiments, differential scanning calorIMetry, leakage of a fluorescent dye and solid-state (31)P- and (2)NMR.

TL;DR: Glycophorin was incorporated into large unilamellar vesicles and the bilayer permeability was measured as a function of the lipid composition and variations in the polar headgroups by incorporation of DOPE, DOPS and, to a lesser extent, cholesterol restored the barrier function.

TL;DR: All analogues tested remained exclusively localized in the outer membrane thereby suggesting that additional (extramitochondrial) factors are required to initiate transfer of PC to the inner membrane.