B. de Kruijff

TL;DR: These experiments prove that the polyene antibiotics form complexes with cholesterol in the A. laidlawii cell membrane, and it is suggested that filipin interacts first with cholesterol throughout the membrane forming primary Filipin-cholesterol complexes.

TL;DR: It is found that incorporation of 0-30 mol% cholesterol does not significantly affect the size of the vesicle whereas above 30 mol%olesterol the sizes of all phosphatidylcholine vesicles sharply increases, the increase in size is the largest for the more saturated phosphatido-choline species.

TL;DR: An in vitro transcription-translation and translocation system is developed to study the transport of PhoE protein and shows that the protein is synthesized as a larger precursor, which can be processed by purified leader peptidase and translocated into inverted inner membrane vesicles.

TL;DR: It was found that at 25 and 37°C rat liver microsomal phosphatidylcholine was completely and rapidly available for replacement by egg phosphate, and vesicles prepared from totalmicrosomal lipids could only be exchanged for about 60%, compared with about 60% with intact microsomes.

TL;DR: Several lipid components of biological membranes preferentially adopt the hexagonal (Hii) phase on hydration, and mixed systems containing bilayer and Hii phase lipids often exhibit novel "lipidic particle" structures which appear to arise from lipids in intrabilayer inverted micellar configurations as discussed by the authors.