Barameht Piralam

TL;DR: Upper airway pneumococcal colonization density among children hospitalized with World Health Organization–defined pneumonia was associated with microbiologically confirmed pneumococCal pneumonia (MCPP) and the optimal colonization density threshold was ≥7 log10 copies/mL.

TL;DR: The NTS isolates causing bloodstream infections in rural Thailand are commonly resistant to ampicillin, cefotaxime, and TMP-SMX, which indicates that serogroup distribution and antibiotic resistance may substantially differ throughout Thailand and the region.

TL;DR: Satisfactory clinical standardization was achieved within and across all PERCH sites, providing reassurance that any etiological or clinical differences observed across the study sites are true differences, and not attributable to differences in application of the clinical case definition, interpretation of clinical signs, or in techniques used for clinical measurements or specimen collection.

TL;DR: Pneumococcal colonization is common among children aged <5 years in Thailand, however, colonization density was not higher among children with severe pneumonia compared to controls, which can inform discussions about PCV introduction and provide baseline data to monitor PCV impact after introduction in Thailand.

TL;DR: The GNNF bacteria are of increasing concern in the clinical setting, and the inability to identify these organisms and determine their AST profiles will impede treatment.