Z
Zhenke Wu
Researcher at University of Michigan
Publications - 52
Citations - 1149
Zhenke Wu is an academic researcher from University of Michigan. The author has contributed to research in topics: Inference & Population. The author has an hindex of 11, co-authored 37 publications receiving 783 citations. Previous affiliations of Zhenke Wu include Johns Hopkins University.
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Journal ArticleDOI
Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study
Katherine L. O'Brien,Henry C. Baggett,W. Abdullah Brooks,Daniel R. Feikin,Laura L. Hammitt,Melissa M. Higdon,Stephen R. C. Howie,Maria Deloria Knoll,Karen L. Kotloff,Orin S. Levine,Shabir A. Madhi,David R. Murdoch,Christine Prosperi,J. Anthony G. Scott,Qiyuan Shi,Donald M. Thea,Zhenke Wu,Scott L. Zeger,Peter V. Adrian,Pasakorn Akarasewi,Trevor P. Anderson,Martin Antonio,Juliet O. Awori,Vicky L. Baillie,Charatdao Bunthi,James Chipeta,Mohammod Jobayer Chisti,Jane Crawley,Andrea DeLuca,Amanda J. Driscoll,Bernard E. Ebruke,Hubert P. Endtz,Nicholas Fancourt,Wei Fu,Doli Goswami,Michelle J. Groome,Meredith Haddix,Lokman Hossain,Yasmin Jahan,E Wangeci Kagucia,Alice Kamau,Ruth A. Karron,Sidi Kazungu,Nana Kourouma,Locadiah Kuwanda,Geoffrey Kwenda,Mengying Li,Eunice M. Machuka,Grant A. Mackenzie,Nasreen Mahomed,Susan A. Maloney,Jessica McLellan,Joanne L. Mitchell,David P. Moore,Susan C. Morpeth,Azwifarwi Mudau,Lawrence Mwananyanda,James Mwansa,Micah Silaba Ominde,Uma Onwuchekwa,Daniel E. Park,Julia Rhodes,Pongpun Sawatwong,Phil Seidenberg,Arifin Shamsul,Eric A. F. Simões,Seydou Sissoko,Somwe Wa Somwe,Samba O. Sow,Mamadou Sylla,Boubou Tamboura,Milagritos D. Tapia,Somsak Thamthitiwat,Aliou Toure,Nora L. Watson,Khalequ Zaman,Syed M. A. Zaman +76 more
TL;DR: Estimating causes of pneumonia in young African and Asian children, using novel analytical methods applied to clinical and microbiological findings, estimated that viruses accounted for 61·4% (95% credible interval [CrI] 57·3–65·6) of causes, whereas bacteria accounted for 27·3% (23·3-31·6).
Journal ArticleDOI
Association of Polygenic Risk Scores for Multiple Cancers in a Phenome-wide Study: Results from The Michigan Genomics Initiative.
Lars G. Fritsche,Lars G. Fritsche,Stephen B. Gruber,Zhenke Wu,Ellen M. Schmidt,Matthew Zawistowski,Stephanie E. Moser,Victoria M. Blanc,Chad M. Brummett,Sachin Kheterpal,Gonçalo R. Abecasis,Bhramar Mukherjee +11 more
TL;DR: Phenome-wide significant associations were observed between PRS and many non-cancer diagnoses, and the idea of "exclusion PRS PheWAS" was introduced to differentiate PRS associations driven by the primary trait from associations arising through shared genetic risk profiles.
Journal ArticleDOI
Lack of response after initial chemoembolization for hepatocellular carcinoma: does it predict failure of subsequent treatment?
Christos S. Georgiades,Jean Francois H. Geschwind,Neil A. Harrison,Andrew Hines-Peralta,Eleni Liapi,Kelvin Hong,Zhenke Wu,Ihab R. Kamel,Constantine Frangakis +8 more
TL;DR: Patients who underwent chemoembolization for HCC showed a response (with both EASL criteria and mRECIST) and improved survival after the second chemoEmbolization treatment, and posttreatment survival of initial nonresponders versus that of initial responders was compared.
Journal ArticleDOI
Density of Upper Respiratory Colonization With Streptococcus pneumoniae and Its Role in the Diagnosis of Pneumococcal Pneumonia Among Children Aged <5 Years in the PERCH Study
Henry C. Baggett,Nora L. Watson,Maria Deloria Knoll,W. Abdullah Brooks,W. Abdullah Brooks,Daniel R. Feikin,Laura L. Hammitt,Stephen R. C. Howie,Stephen R. C. Howie,Stephen R. C. Howie,Karen L. Kotloff,Orin S. Levine,Shabir A. Madhi,Shabir A. Madhi,David R. Murdoch,David R. Murdoch,J. Anthony G. Scott,J. Anthony G. Scott,Donald M. Thea,Martin Antonio,Martin Antonio,Martin Antonio,Juliet O. Awori,Vicky L. Baillie,Vicky L. Baillie,Andrea DeLuca,Amanda J. Driscoll,Julie Duncan,Bernard E. Ebruke,Doli Goswami,Melissa M. Higdon,Ruth A. Karron,David P. Moore,David P. Moore,Susan C. Morpeth,Susan C. Morpeth,Susan C. Morpeth,Justin M Mulindwa,Daniel E. Park,Wantana Paveenkittiporn,Barameht Piralam,Christine Prosperi,Samba O. Sow,Milagritos D. Tapia,Khalequ Zaman,Scott L. Zeger,Katherine L. O'Brien,Nicholas Fancourt,Wei Fu,E Wangeci Kagucia,Mengying Li,Zhenke Wu,Jane Crawley,Hubert P. Endtz,Lokman Hossain,Yasmin Jahan,Hasan Ashraf,Jessica McLellan,Eunice Machuka,Arifin Shamsul,Syed M. A. Zaman,Grant A. Mackenzie,Alice Kamau,Sidi Kazungu,Micah Silaba Ominde,Mamadou Sylla,Boubou Tamboura,Uma Onwuchekwa,Nana Kourouma,Aliou Toure,Peter V. Adrian,Locadiah Kuwanda,Azwifarwi Mudau,Michelle J. Groome,Nasreen Mahomed,Somsak Thamthitiwat,Susan A. Maloney,Charatdao Bunthi,Julia Rhodes,Pongpun Sawatwong,Pasakorn Akarasewi,Lawrence Mwananyanda,James Chipeta,Phil Seidenberg,James Mwansa,Somwe Wa Somwe,Geoffrey Kwenda,Trevor P. Anderson,Joanne L. Mitchell +88 more
TL;DR: Upper airway pneumococcal colonization density among children hospitalized with World Health Organization–defined pneumonia was associated with microbiologically confirmed pneumococCal pneumonia (MCPP) and the optimal colonization density threshold was ≥7 log10 copies/mL.
Journal ArticleDOI
Association of C-Reactive Protein With Bacterial and Respiratory Syncytial Virus–Associated Pneumonia Among Children Aged <5 Years in the PERCH Study
Melissa M. Higdon,Tham T Le,Tham T Le,Katherine L. O'Brien,David R. Murdoch,David R. Murdoch,Christine Prosperi,Henry C. Baggett,W. Abdullah Brooks,W. Abdullah Brooks,Daniel R. Feikin,Daniel R. Feikin,Laura L. Hammitt,Laura L. Hammitt,Stephen R. C. Howie,Stephen R. C. Howie,Stephen R. C. Howie,Karen L. Kotloff,Orin S. Levine,Orin S. Levine,J. Anthony G. Scott,J. Anthony G. Scott,Donald M. Thea,Juliet O. Awori,Vicky L. Baillie,Vicky L. Baillie,Stephanie Cascio,Somchai Chuananon,Andrea DeLuca,Amanda J. Driscoll,Bernard E. Ebruke,Hubert P. Endtz,Hubert P. Endtz,Anek Kaewpan,Geoff Kahn,Angela Karani,Ruth A. Karron,David P. Moore,David P. Moore,Daniel E. Park,Daniel E. Park,Mohammed Ziaur Rahman,Rasheed Salaudeen,Rasheed Salaudeen,Phil Seidenberg,Phil Seidenberg,Somwe Wa Somwe,Mamadou Sylla,Milagritos D. Tapia,Scott L. Zeger,Maria Deloria Knoll,Shabir A. Madhi,Shabir A. Madhi,Nicholas Fancourt,Wei Fu,E Wangeci Kagucia,Mengying Li,Zhenke Wu,Nora L. Watson,Jane Crawley,Khalequ Zaman,Doli Goswami,Lokman Hossain,Yasmin Jahan,Hasan Ashraf,Martin Antonio,Jessica McLellan,Eunice M. Machuka,Arifin Shamsul,Syed M. A. Zaman,Grant A. Mackenzie,Susan C. Morpeth,Alice Kamau,Sidi Kazungu,Micah Silaba Ominde,Samba O. Sow,Boubou Tamboura,Uma Onwuchekwa,Nana Kourouma,Aliou Toure,Peter V. Adrian,Locadiah Kuwanda,Azwifarwi Mudau,Michelle J. Groome,Nasreen Mahomed,Somsak Thamthitiwat,Susan A. Maloney,Charatdao Bunthi,Julia Rhodes,Pongpun Sawatwong,Pasakorn Akarasewi,Lawrence Mwananyanda,James Chipeta,James Mwansa,Geoffrey Kwenda,Trevor P. Anderson,Joanne L. Mitchell +96 more
TL;DR: Elevated CRP was positively associated with confirmed bacterial pneumonia and negatively associated with RSV pneumonia in PERCH, suggesting CRP may be useful for distinguishing bacterial from RSV-associated pneumonia, although its role in discriminating against other respiratory viral- associated pneumonia needs further study.