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Barbara Garmy-Susini

Researcher at University of Toulouse

Publications -  68
Citations -  3840

Barbara Garmy-Susini is an academic researcher from University of Toulouse. The author has contributed to research in topics: Lymphangiogenesis & Lymphatic system. The author has an hindex of 25, co-authored 63 publications receiving 3176 citations. Previous affiliations of Barbara Garmy-Susini include Paul Sabatier University & French Institute of Health and Medical Research.

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Integrins in angiogenesis and lymphangiogenesis

TL;DR: The evidence implicating integrins as a family of fundamental regulators of angiogenesis and lymphangiogenesis is reviewed, and several integrin-targeted therapeutic agents are currently in clinical trials for cancer therapy.
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Chemotherapy Resistant Human Acute Myeloid Leukemia Cells are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

TL;DR: It is demonstrated that essential mitochondrial functions contribute to AraC resistance in AML and are a robust hallmark of AraC sensitivity and a promising therapeutic avenue to treat AML residual disease.
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Integrin α4β1–VCAM-1–mediated adhesion between endothelial and mural cells is required for blood vessel maturation

TL;DR: It is shown that integrin alpha4beta1 (VLA-4) and VCAM-1 promote close intercellular adhesion between ECs and pericytes and that this interaction is required for blood vessel formation.
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Relevance of sexual dimorphism to regulatory T cells: estradiol promotes IFN-γ production by invariant natural killer T cells

TL;DR: These results provide the first evidence that estrogens influence iNKT cells leading to this gender dimorphism in their cytokine production profile, as well as supporting a crucial role of ovarian hormones in this phenomenon.
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Integrin α4β1 Signaling Is Required for Lymphangiogenesis and Tumor Metastasis

TL;DR: The studies show that integrin alpha4beta1 and the signals it transduces regulate the adhesion, migration, invasion, and survival of proliferating lymphatic endothelial cells.