Bart Theelen

TL;DR: The authors showed that dectin-1 signaling in response to fungi and mycobacteria induces IL-1β maturation via a noncanonical caspase-8-dependent inflammasome.

TL;DR: MALDI-TOF mass spectrometry readily distinguishes the newly recognized species, which differ in aspects of pathogenicity, prevalence for patient groups, as well as biochemical and physiological aspects, such as susceptibility to antifungals.

TL;DR: The authors propose the existence of two species, C. neoformans (Sanfelice) Vuillemin and C. bacillisporus Kwon-Chung, which differ in geographical distribution, serotypes and ecological origin, and within each species three AFLP genotypes occur.

TL;DR: Nine genera were emended to include anamorphic and teleomorphic species based on the results obtained by a multi-gene phylogenetic analysis, phylogenetic network analyses, branch length-based methods, as well as morphological, physiological and biochemical comparisons.

TL;DR: The new species and the new variety have a multiresistant antifungal profile, which includes high MICs of amphotericin B and cross-resistance to azole compounds and should be based on molecular methods, such as sequence analysis of ITS regions and matrix-assisted laser desorption ionization–time of flight mass spectrometry.