B
Bas Verbruggen
Researcher at University of Exeter
Publications - 7
Citations - 367
Bas Verbruggen is an academic researcher from University of Exeter. The author has contributed to research in topics: White spot syndrome & Reproductive success. The author has an hindex of 5, co-authored 6 publications receiving 231 citations.
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Journal ArticleDOI
Molecular Mechanisms of White Spot Syndrome Virus Infection and Perspectives on Treatments.
Bas Verbruggen,Lisa K. Bickley,Ronny van Aerle,Kelly S. Bateman,Grant D. Stentiford,Eduarda M. Santos,Charles R. Tyler +6 more
TL;DR: Current knowledge of how WSSV infects and replicates in its host, and critique strategies for WSD treatment are assessed.
Journal ArticleDOI
Pharmacology beyond the patient - The environmental risks of human drugs.
Lina Gunnarsson,Jason Snape,Bas Verbruggen,Stewart F. Owen,Erik Kristiansson,Luigi Margiotta-Casaluci,Tobias Österlund,Kathryn Hutchinson,Dean Leverett,Becky Marks,Charles R. Tyler +10 more
TL;DR: It is shown that presence/absence of drug-target orthologues are predictive of susceptible species for the more potent drugs, and for most drugs with a full set of ecotoxicity data, risk quotients assuming worst-case exposure assessments were below one in all European countries indicating low environmental risks for the endpoints assessed.
Journal ArticleDOI
ECOdrug: a database connecting drugs and conservation of their targets across species.
Bas Verbruggen,Lina-Maria Gunnarsson,Erik Kristiansson,Tobias Österlund,Stewart F. Owen,Jason Snape,Jason Snape,Charles R. Tyler +7 more
TL;DR: A new research platform tool, ECOdrug, is introduced that reliably connects drugs to their protein targets across divergent species and harmonizes ortholog predictions from multiple sources via a simple user interface underpinning critical applications for a wide range of studies in pharmacology, ecotoxicology and comparative evolutionary biology.
Journal ArticleDOI
De novo assembly of the Carcinus maenas transcriptome and characterization of innate immune system pathways
Bas Verbruggen,Lisa K. Bickley,Eduarda M. Santos,Charles R. Tyler,Grant D. Stentiford,Kelly S. Bateman,Ronny van Aerle +6 more
TL;DR: An assembled transcriptome for C. maenas has revealed the presence of a series of known targets and functional pathways that form part of their innate immune system and illustrate tissue specific differences in their expression patterns.
Journal ArticleDOI
Exposure to an anti-androgenic herbicide negatively impacts reproductive physiology and fertility in Xenopus tropicalis.
Frances Orton,Moa Säfholm,Erika Jansson,Ylva Carlsson,Andreas Eriksson,Jerker Fick,T. Uren Webster,T. McMillan,M. Leishman,Bas Verbruggen,Theodoros Economou,Charles R. Tyler,Cecilia Berg +12 more
TL;DR: The findings advance understanding of reproductive biology of X. tropicalis and illustrate negative effects of linuron on reproductive processes at a concentration measured in freshwater environments.