B
Bastien Castagner
Researcher at McGill University
Publications - 28
Citations - 1117
Bastien Castagner is an academic researcher from McGill University. The author has contributed to research in topics: Gut flora & Inositol. The author has an hindex of 13, co-authored 24 publications receiving 974 citations. Previous affiliations of Bastien Castagner include École Polytechnique Fédérale de Lausanne & ETH Zurich.
Papers
More filters
PatentDOI
Automated oligosaccharide synthesizer
TL;DR: This tutorial review defines the state of the art of automated solid phase oligosaccharide synthesis and identifies areas in need of further innovation.
Journal ArticleDOI
Streamlined access to conjugation-ready glycans by automated synthesis
Lenz Kröck,Davide Esposito,Bastien Castagner,Cheng-Chung Wang,Pascal Bindschädler,Peter H. Seeberger,Peter H. Seeberger +6 more
TL;DR: A versatile platform integrating a new synthesis strategy and a fully-automated oligosaccharide synthesizer is described, which produced biologically-significant oligosACcharides of increasing length, structural complexity, and chemical diversity.
Journal ArticleDOI
Automated Synthesis of the Tumor-Associated Carbohydrate Antigens Gb-3 and Globo-H: Incorporation of α-Galactosidic Linkages
TL;DR: The Globo series of tumor-associated antigens are glycosphingolipids implicated in several cancer types and contain an α-linked galactose, and methods to efficiently install cis-galactosidic linkages by automated solid-phase oligosaccharide synthesis are reported.
Journal ArticleDOI
Combined Approaches to the Synthesis and Study of Glycoproteins
TL;DR: Recent advances in glycobiology are highlighted with a particular emphasis on oligosaccharide synthesis and conjugation techniques for the construction of homogeneous glycoconjugates for the study of protein-glycan interactions.
Journal ArticleDOI
Automated Solid-Phase Synthesis of Protected Oligosaccharides Containing β-Mannosidic Linkages
TL;DR: This is the first automated solid-phase synthesis of oligosaccharides containing the challenging beta-mannosidic linkage, and the methods described here expand the scope of carbohydrates currently accessible by automation as many oligosACcharides of biological interest contain beta-Mannoside linkages.