Bennard van Ravenzwaay

TL;DR: Toxicity and dustiness data can be used to compare different MWCNT materials and to select the material with the lowest risk potential for a given application, but nonetheless strict industrial hygiene measures must be taken during handling and processing.

TL;DR: In this study, the predictivities of four in vitro assays, one in chemico and one in silico method addressing three different steps in the development of skin sensitization were assessed using 54 test substances of known sensitizing potential and used to develop an in vitro testing scheme and prediction model for the detection of skin sensitizers.

TL;DR: Three working groups addressing questions regarding 1) metabolomics for in vitro studies 2) the appropriate use of metabolomics in systems toxicology, and 3) use of metabolites in a regulatory context are addressed.

TL;DR: The pulmonary effects of nano-TiO2 observed in this short-term study were comparable to those previously reported in subchronic inhalation studies.

TL;DR: Until the properties which govern the toxicity are identified, testing by short-term inhalation is the best option to identify hazardous properties in order to avoid unsafe applications or select safer alternatives for a given application.