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Berna Beverloo
Researcher at Erasmus University Medical Center
Publications - 45
Citations - 1835
Berna Beverloo is an academic researcher from Erasmus University Medical Center. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 16, co-authored 39 publications receiving 1688 citations. Previous affiliations of Berna Beverloo include Boston Children's Hospital & Erasmus University Rotterdam.
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Journal ArticleDOI
CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer
Hui Ling,Riccardo Spizzo,Yaser Atlasi,Milena S. Nicoloso,Masayoshi Shimizu,Roxana S. Redis,Roxana S. Redis,Naohiro Nishida,Naohiro Nishida,Roberta Gafà,Jian Song,Zhiyi Guo,Cristina Ivan,Elisa Barbarotto,Ingrid de Vries,Xinna Zhang,Manuela Ferracin,Mike Churchman,Janneke F. van Galen,Berna Beverloo,Maryam Shariati,Franziska Haderk,Franziska Haderk,Marcos R. Estecio,Guillermo Garcia-Manero,Gijs A. Patijn,David C. Gotley,Vikas Bhardwaj,Imad Shureiqi,Subrata Sen,Asha S. Multani,James W. Welsh,Ken Yamamoto,Itsuki Taniguchi,Min-Ae Song,Steven Gallinger,Graham Casey,Stephen N. Thibodeau,Loic Le Marchand,Maarit Tiirikainen,Sendurai A. Mani,Wei Zhang,Ramana V. Davuluri,Koshi Mimori,Masaki Mori,Anieta M. Sieuwerts,John W.M. Martens,Ian Tomlinson,Massimo Negrini,Ioana Berindan-Neagoe,John A. Foekens,Stanley R. Hamilton,Giovanni Lanza,Scott Kopetz,Riccardo Fodde,George A. Calin +55 more
TL;DR: The results support a new mechanism of MYC and WNT regulation by the novel lncRNA CCAT2 in colorectal cancer pathogenesis, and provide an alternative explanation of the SNP-conferred cancer risk.
Journal ArticleDOI
Mutations in a TGF-β ligand, TGFB3, cause syndromic aortic aneurysms and dissections.
Aida M. Bertoli-Avella,Elisabeth Gillis,Hiroko Morisaki,Judith M.A. Verhagen,Bianca M. de Graaf,Gerarda van de Beek,Elena M. Gallo,Boudewijn P.T. Kruithof,Hanka Venselaar,Loretha Myers,Steven Laga,Alexander J Doyle,Gretchen L. Oswald,Gert W. A. van Cappellen,Itaru Yamanaka,Robert van der Helm,Berna Beverloo,Annelies de Klein,Luba M. Pardo,Martin Lammens,Christina Evers,Koenraad Devriendt,Michiel Dumoulein,Janneke Timmermans,Hennie T. Brüggenwirth,Frans W. Verheijen,Inez Rodrigus,Gareth Baynam,Marlies Kempers,Johan Saenen,Emeline M. Van Craenenbroeck,Kenji Minatoya,Ritsu Matsukawa,Takuro Tsukube,Noriaki Kubo,Robert M.W. Hofstra,Marie J ose Goumans,Jos A. Bekkers,Jolien W. Roos-Hesselink,Ingrid M.B.H. van de Laar,Harry C. Dietz,Lut Van Laer,Takayuki Morisaki,Marja W. Wessels,Bart Loeys +44 more
TL;DR: In this article, aneurysms affecting the aorta are a common condition associated with high mortality as a result of aortic dissection or rupture, and investigations of the pathogenic mechanisms invo...
Journal Article
Clinical, molecular, and prognostic significance of WHO type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and various other 3q abnormalities in acute myeloid leukemia: A study of 6,515 cases of AML
S Groeschel,Sanne Lugthart,Berna Beverloo,Sabine Kayser,Peter J. M. Valk,S. L Van Zelderen-Bhola,G-J Ossenkoppele,Edo Vellenga,E van den Berg-de Ruiter,Urs Schanz,Gregor Verhoef,Augustin Ferrant,C-H Koehne,Michael Pfreundschuh,H-A Horst,Elisabeth Koller,M. von Lilienfeld-Toal,Martin Bentz,Arnold Ganser,Brigitte Schlegelberger,Martine Jotterand,Jürgen Krauter,Thomas Pabst,Matthias Theobald,Richard F. Schlenk,Ruud Delwel,Konstanze Doehner,Bob Löwenberg,Hartmut Doehner +28 more
TL;DR: Various categories of 3q abnormalities in AML can be distinguished according to their clinical, hematologic, and genetic features.
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The structure‐specific endonuclease Ercc1—Xpf is required for targeted gene replacement in embryonic stem cells
Laura J. Niedernhofer,Jeroen Essers,Geert Weeda,Berna Beverloo,Jan de Wit,Manja Muijtjens,Hanny Odijk,Jan H.J. Hoeijmakers,Roland Kanaar +8 more
TL;DR: It is demonstrated that although Ercc1 is dispensable for recombination between sister chromatids, it is essential for targeted gene replacement in mouse embryonic stem cells and a model for the mechanism of targeted gene Replacement is proposed that invokes a role for ErCC1—Xpf in making the recipient genomic locus receptive for gene replacement.
Journal ArticleDOI
Restricted 12p Amplification and RAS Mutation in Human Germ Cell Tumors of the Adult Testis
Helene Roelofs,M.C. Mostert,Kirsten Pompe,Gaetano Zafarana,Monique van Oorschot,Ruud J.H.L.M. van Gurp,Ad J. M. Gillis,Hans Stoop,Berna Beverloo,J. Wolter Oosterhuis,Carsten Bokemeyer,Leendert H. J. Looijenga +11 more
TL;DR: The model that gain of 12p in TGCTs is related to invasive growth allows tumor cells, in particular those showing characteristics of early germ cells (ie, the seminoma cells), to survive outside their specific microenvironment.