B
Bernard Grosbois
Researcher at University of Rennes
Publications - 127
Citations - 5100
Bernard Grosbois is an academic researcher from University of Rennes. The author has contributed to research in topics: Multiple myeloma & Monoclonal gammopathy of undetermined significance. The author has an hindex of 32, co-authored 127 publications receiving 4767 citations. Previous affiliations of Bernard Grosbois include University of Toulouse.
Papers
More filters
Journal ArticleDOI
Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome
Hervé Avet-Loiseau,Michel Attal,Philippe Moreau,Catherine Charbonnel,Frédéric Garban,Cyrille Hulin,Serge Leyvraz,Mauricette Michallet,Ibrahim Yakoub-Agha,Laurent Garderet,Gerald Marit,Lucienne Michaux,Laurent Voillat,Marc Renaud,Bernard Grosbois,Gaelle Guillerm,Lotfi Benboubker,Mathieu Monconduit,Catherine Thieblemont,Philippe Casassus,Denis Caillot,Anne-Marie Stoppa,Jean-Jacques Sotto,Marc Wetterwald,Charles Dumontet,Jean-Gabriel Fuzibet,Isabelle Azais,Véronique Dorvaux,Marc Zandecki,Régis Bataille,Stephane Minvielle,Jean-Luc Harousseau,Thierry Facon,Claire Mathiot +33 more
TL;DR: In myeloma, the genomic aberrations t(4;14) and del(17p), together with beta2-microglobulin level, are important independent predictors of survival and have implications for the design of risk-adapted treatment strategies.
Journal ArticleDOI
Comparison of 200 mg/m2 melphalan and 8 Gy total body irradiation plus 140 mg/m2 melphalan as conditioning regimens for peripheral blood stem cell transplantation in patients with newly diagnosed multiple myeloma: final analysis of the Intergroupe Francophone du Myélome 9502 randomized trial
Philippe Moreau,Thierry Facon,Michel Attal,Cyrille Hulin,Mauricette Michallet,Frédéric Maloisel,Jean-Jacques Sotto,François Guilhot,Gerald Marit,Chantal Doyen,Jérôme Jaubert,Jean-Gabriel Fuzibet,Sylvie François,Lotfi Benboubker,M. Monconduit,Laurent Voillat,Margaret Macro,Christian Berthou,Véronique Dorvaux,Bernard Pignon,Bernard Rio,Thomas Matthes,Philippe Casassus,Denis Caillot,Norbert Najman,Bernard Grosbois,Régis Bataille,Jean-Luc Harousseau +27 more
TL;DR: In this article, the authors compared the two most widely used conditioning regimens before autologous stem cell transplantation in newly diagnosed symptomatic patients younger than 65 years old: 8 Gy total body irradiation plus 140 mg/m2 melphalan (arm A) versus 200 mg /m2melphalan(arm B).
Journal ArticleDOI
High-dose melphalan versus melphalan plus dexamethasone for AL amyloidosis.
Arnaud Jaccard,Philippe Moreau,Véronique Leblond,Xavier Leleu,Lofti Benboubker,Olivier Hermine,Christian Recher,Bouchra Asli,Bruno Lioure,Bruno Royer,Fabrice Jardin,Franck Bridoux,Bernard Grosbois,Jérôme Jaubert,Jean-Charles Piette,Pierre Ronco,Fabrice Quet,Michel Cogné,Jean-Paul Fermand +18 more
TL;DR: The outcome of treatment of AL amyloidosis with high-doseMelphalan plus autologous stem-cell rescue was not superior to the outcome with standard-dose melphalanplus dexamethasone.
Journal ArticleDOI
Anti-HMGCR autoantibodies in European patients with autoimmune necrotizing myopathies: inconstant exposure to statin.
Yves Allenbach,Laurent Drouot,Aude Rigolet,Jean Luc Charuel,Fabienne Jouen,Norma B. Romero,Thierry Maisonobe,Odile Dubourg,Anthony Behin,Pascal Laforêt,T. Stojkovic,Bruno Eymard,Nathalie Costedoat-Chalumeau,Emmanuelle Campana-Salort,Anne Tournadre,Lucile Musset,Brigitte Bader-Meunier,Isabelle Koné-Paut,Jean Sibilia,Laurent Servais,Olivier Fain,Claire Larroche,Elisabeth Diot,Benjamin Terrier,Raphael De Paz,Antoine Dossier,Dominique Menard,Chafika Morati,Marielle Roux,Xavier Ferrer,Jérémie Martinet,Sophie Besnard,Rémi Bellance,Patrice Cacoub,Laurent Arnaud,Bernard Grosbois,Serge Herson,Olivier Boyer,Olivier Benveniste +38 more
TL;DR: This study confirms the observation and description of anti-HMGCR aAb associated with NAM, and titers correlated with CK levels and muscle strength, suggesting their pathogenic role.
Journal Article
14q32 translocations and monosomy 13 observed in monoclonal gammopathy of undetermined significance delineate a multistep process for the oncogenesis of multiple myeloma. Intergroupe Francophone du Myélome.
Hervé Avet-Loiseau,Thierry Facon,Axelle Daviet,Catherine Godon,M. J. Rapp,Jean-Luc Harousseau,Bernard Grosbois,Régis Bataille +7 more
TL;DR: Fluorescence in situ hybridization experiments with probes directed to the 14q32 and 13q14 chromosomal regions are performed to elaborate a plasma cell oncogenesis model from MGUS to MM.