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Brian R. Davidson
Researcher at University College London
Publications - 591
Citations - 24232
Brian R. Davidson is an academic researcher from University College London. The author has contributed to research in topics: Liver transplantation & Transplantation. The author has an hindex of 75, co-authored 557 publications receiving 21214 citations. Previous affiliations of Brian R. Davidson include Royal Free Hospital & Leicester Royal Infirmary.
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Evaluation of the POSSUM Scoring System for Comparative Audit in Pancreatic Surgery
TL;DR: While P-POSSUM appeared satisfactory for predicting mortality risk, POSSUM overestimated morbidity and mortality for PD in a specialist centre.
Journal ArticleDOI
Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.
Nathalie M. Schmidt,Peter A C Wing,Mariana O. Diniz,Laura J. Pallett,Leo Swadling,James Harris,Alice R Burton,Anna Jeffery-Smith,Nekisa Zakeri,Oliver E. Amin,Stephanie Kucykowicz,Mirjam H.M. Heemskerk,Brian R. Davidson,Brian R. Davidson,Tim Meyer,Tim Meyer,Joe Grove,Hans J. Stauss,Ines Pineda-Torra,Clare Jolly,Elizabeth C. Jury,Jane A. McKeating,Mala K. Maini +22 more
TL;DR: In this article, the authors showed that ACAT inhibition has antiviral activity against hepatitis B (HBV), as well as boosting protective anti-HBV and anti-hepatocellular carcinoma (HCC) T cells.
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T Cells Infiltrating Diseased Liver Express Ligands for the NKG2D Stress Surveillance System.
W.-C. Huang,Nicholas Easom,Xin-Zi Tang,Upkar S. Gill,H Singh,Francis P. Robertson,Chiwen Chang,John Trowsdale,Brian R. Davidson,William Rosenberg,Giuseppe Fusai,Antoine Toubert,Patrick T F Kennedy,Dimitra Peppa,Mala K. Maini +14 more
TL;DR: This is the first ex vivo demonstration that non-virally infected human T cells can expressNKG2DL, with implications for stress surveillance by the large number of NKG2D-expressing NK cells sequestered in the liver.
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Effect of remote ischemic preconditioning on liver ischemia/reperfusion injury using a new mouse model.
Mahmoud Abu-Amara,Shi Yu Yang,Alberto Quaglia,Peter Rowley,Niteen Tapuria,Alexander M. Seifalian,Barry Fuller,Brian R. Davidson +7 more
TL;DR: A validated mouse model of hindlimb RIPC that attenuates liver IR injury and reduced plasma aminotransferases and histopathological and ultrastructural features of injury is described.
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Cholecystectomy for suspected gallbladder dyskinesia
TL;DR: The evidence for the benefits and harms of cholecystectomy in gallbladder dyskinesia from randomised clinical trials is based on a single small trial at risk of bias, and further randomisedclinical trials with improved bias control are necessary to confirm or reject the promising results.