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Brian W. J. Mahy
Researcher at Centers for Disease Control and Prevention
Publications - 7
Citations - 2087
Brian W. J. Mahy is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Hantavirus & Respiratory disease. The author has an hindex of 7, co-authored 7 publications receiving 1979 citations.
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Journal ArticleDOI
Nipah Virus: A Recently Emergent Deadly Paramyxovirus
Kaw Bing Chua,William J. Bellini,Paul A. Rota,Brian H. Harcourt,Azaibi Tamin,Sai Kit Lam,Thomas G. Ksiazek,Pierre E. Rollin,Sherif R. Zaki,Wun-Ju Shieh,Cynthia S. Goldsmith,Duane J. Gubler,John T. Roehrig,Bryan T. Eaton,A. R. Gould,James G. Olson,P. Daniels,Ai Ee Ling,Clarence J. Peters,Larry J. Anderson,Brian W. J. Mahy +20 more
TL;DR: Electron microscopic, serologic, and genetic studies indicate that the Nipah virus belongs to the family Paramyxoviridae and is most closely related to the recently discovered Hendra virus, and it is suggested that these two viruses are representative of a new genus within the familyparamyxviridae.
Journal Article
Hantavirus Pulmonary Syndrome: Pathogenesis of an Emerging Infectious Disease
Sherif R. Zaki,Patricia W. Greer,L M Coffield,Cynthia S. Goldsmith,Kurt B. Nolte,Kathy Foucar,Richard M. Feddersen,Ross E. Zumwalt,Gayle L. Miller,Ali S. Khan,Pierre E. Rollin,Thomas G. Ksiazek,Stuart T. Nichol,Brian W. J. Mahy,Clarence J. Peters +14 more
TL;DR: Pulmonary histopathological features were similar in most of the fatal HPS cases and consisted of an interstitial pneumonitis with a variable mononuclear cell infiltrate, edema, and focal hyaline membranes, however, pulmonary features were significantly different and included diffuse alveolar damage and variable degrees of severe air space disorganization.
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Identification of a new North American hantavirus that causes acute pulmonary insufficiency
Thomas G. Ksiazek,Clarence J. Peters,Pierre E. Rollin,Sherif R. Zaki,Stuart T. Nichol,Christina F. Spiropoulou,Sergei Morzunov,Heinz Feldmann,Anthony Sanchez,Ali S. Khan,Brian W. J. Mahy,Kaye Wachsmuth,Jay C. Butler +12 more
TL;DR: This newly recognized hantavirus causes a novel syndrome of acute pulmonary edema and shock; the pathogenesis is related to the presence of virus antigens in the pulmonary capillaries.
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An approach to the control of disease transmission in pig-to-human xenotransplantation
David E. Onions,David K. C. Cooper,Tom J.L. Alexander,Corrie C. Brown,Erwin A.W. Claassen,J. Foweraker,Delbert L.Hank Harris,Brian W. J. Mahy,P.D. Minor,Albert D. M. E. Osterhaus,Paul-Pierre Pastoret,Kazuya Yamanouchi +11 more
TL;DR: The likelihood of achieving the aim of excluding infectious agents from the organ‐source pigs, the potential means by which it may best be achieved, and the potential consequences for the health of others in the community are discussed.
Journal ArticleDOI
Reemergence of Ebola virus in Africa.
Anthony Sanchez,Thomas G. Ksiazek,Pierre E. Rollin,C. J. Peters,Stuart T. Nichol,Ali S. Khan,Brian W. J. Mahy +6 more
TL;DR: The new Ebola virus recently isolated from a patient in the Côte d’Ivoire has been shown to be genetically distinct from previous Ebola isolates (A. Sanchez, unpublished data) and is the first evidence of Ebola virus in West Africa.