Bungo Furusato

TL;DR: The classification working group of the International Society of Urological Pathology consensus conference on renal neoplasia was in charge of making recommendations regarding additions and changes to the current World Health Organization Classification of Renal Tumors, with consensus that 5 entities should be recognized as new distinct epithelial tumors within the classification system.

TL;DR: The International Society of Urological Pathology 2012 Consensus Conference made recommendations regarding classification, prognostic factors, staging, and immunohistochemical and molecular assessment of adult renal tumors.

TL;DR: It is shown here that human telomerase reverse transcriptase (hTERT)-immortalized primary nonmalignant and malignant tumor-derived human prostate epithelial cell lines retain stem cell properties with a CD133(+) phenotype, and immunostaining of clinical prostate specimens showed that CD133 expression was detected in a subpopulation of prostate cancer cells and corresponded to the loss of AR.

TL;DR: Quantitative proteomic profiling utilizing stable isotope labeling confirmed similar expression levels of prostate-specific antigen and prostatic acid phosphatase in BPH and PCa cells, whereas the expression of macrophage inhibitory cytokine-1 was found to be greater in PCa as compared with BPH cells.

TL;DR: In this paper, a review of the current knowledge of CXCR4 regulation and how deregulation of this protein may contribute to the progression of cancer is presented, focusing on the current state of the art.