Asli Yilmaz

TL;DR: The classification working group of the International Society of Urological Pathology consensus conference on renal neoplasia was in charge of making recommendations regarding additions and changes to the current World Health Organization Classification of Renal Tumors, with consensus that 5 entities should be recognized as new distinct epithelial tumors within the classification system.

TL;DR: The International Society of Urological Pathology 2012 Consensus Conference made recommendations regarding classification, prognostic factors, staging, and immunohistochemical and molecular assessment of adult renal tumors.

TL;DR: Although this tumor may undergo dedifferentiation and metastasize, sometimes after a prolonged delay, metastatic disease is rare in the absence of high-grade nuclear atypia or coagulative necrosis and showing a strong relationship with SDH germline mutation.

TL;DR: The role of biomarkers in the diagnosis and assessment of prognosis of renal tumors is addressed and the use of immunohistochemical markers and the approach to specific differential diagnostic scenarios is focused upon.

TL;DR: It is proposed that sporadic “eosinophilic, solid, and cystic RCC,” which occurs predominantly in female individuals and is characterized by distinct morphologic features, predominant CK20-positive/CK7-negative immunophenotype, and indolent behavior, represents a novel subtype of RCC.