C
C Cuny
Researcher at Robert Koch Institute
Publications - 25
Citations - 1813
C Cuny is an academic researcher from Robert Koch Institute. The author has contributed to research in topics: Methicillin-resistant Staphylococcus aureus & Staphylococcus aureus. The author has an hindex of 17, co-authored 24 publications receiving 1775 citations. Previous affiliations of C Cuny include National Institute for Health and Welfare.
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Journal ArticleDOI
Harmonization of pulsed-field gel electrophoresis protocols for epidemiological typing of strains of methicillin-resistant Staphylococcus aureus: a single approach developed by consensus in 10 European laboratories and its application for tracing the spread of related strains.
Stephen Murchan,Mary E. Kaufmann,Ariane Deplano,Raf De Ryck,Marc Struelens,Christina Elsberg Zinn,Vivian Fussing,Saara Salmenlinna,Jaana Vuopio-Varkila,Névine El Solh,C Cuny,Wolfgang Witte,Panayotis T. Tassios,N. J. Legakis,Willem B. van Leeuwen,Alex van Belkum,A. Vindel,Idoia Laconcha,Javier Garaizar,Saara Haeggman,Barbro Olsson-Liljequist,Ulrika Ransjo,Geoffrey Coombes,Barry Cookson +23 more
TL;DR: This multinational European Union project has established for the first time a European database of representative epidemic MRSA (EMRSA) strains and has compared them by using a new “harmonized” PFGE protocol developed by a consensus approach that has demonstrated sufficient reproducibility to allow the successful comparison of pulsed-field gels between laboratories and the tracking of strains around the EU.
Journal ArticleDOI
Livestock-associated Methicillin-Resistant Staphylococcus aureus in Humans, Europe
Brigitte A. G. L. van Cleef,Dominique L Monnet,Andreas Voss,Karina K. Krziwanek,Franz Allerberger,Marc Struelens,Helena H. Zemlickova,Robert Skov,Jaana Vuopio-Varkila,C Cuny,Alexander W. Friedrich,Iris Spiliopoulou,Judit J. Pászti,Hjordis Hardardottir,Angela S. Rossney,Angelo A. Pan,Annalisa Pantosti,Michael M. Borg,Hajo Grundmann,Manica M. Mueller-Premru,Barbro Olsson-Liljequist,Andreas A. Widmer,Stephan Harbarth,Alexander A. Schweiger,Serhat Ünal,Jan Kluytmans +25 more
TL;DR: To estimate the proportion of methicillin-resistant Staphylococcus aureus (MRSA) isolates from humans that were sequence type (ST) 398, 24 laboratories in 17 countries in Europe in 2007 were surveyed.
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Evaluation of Molecular Typing Methods in Characterizing a European Collection of Epidemic Methicillin-Resistant Staphylococcus aureus Strains: the HARMONY Collection
Barry Cookson,D. Ashley Robinson,Alastair B. Monk,Stephen Murchan,Ariane Deplano,Rafael De Ryck,Marc Struelens,Christina Scheel,Vivian Fussing,Saara Salmenlinna,Jaana Vuopio-Varkila,C Cuny,Wolfgang Witte,Panayotis T. Tassios,N. J. Legakis,Willem B. van Leeuwen,Alex van Belkum,A. Vindel,Javier Garaizar,Sara Hæggman,Barbro Olsson-Liljequist,Ulrika Ransjo,Manica Müller-Premru,Waleria Hryniewicz,Angela S. Rossney,Brian O'Connell,Benjamin R. D. Short,Jonathan C. Thomas,Simon J. O’Hanlon,Mark C. Enright +29 more
TL;DR: It is demonstrated that the integration of such technologies is achievable, although common protocols (such as those developed for PFGE) may also be important, as is the use of centralized Internet sites to facilitate data analysis.
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Emergence of methicillin-resistant Staphylococcus aureus with Panton–Valentine leukocidin genes in central Europe
Wolfgang Witte,C Braulke,C Cuny,Birgit Strommenger,Guido Werner,D Heuck,Uta Jappe,Constanze Wendt,H.-J. Linde,Dag Harmsen +9 more
TL;DR: Investigation of strains of methicillin-resistant Staphylococcus aureus for the presence of the lukS–lukF determinant of Panton–Valentine leukocidin and to further characterize strains found to contain the genes revealed a unique pattern of genomic typing.
Journal ArticleDOI
PCR for the identification of methicillin-resistant Staphylococcus aureus (MRSA) strains using a single primer pair specific for SCCmec elements and the neighbouring chromosome-borne orfX.
C Cuny,Wolfgang Witte +1 more
TL;DR: The chromosomal location of the SCCmec elements containing mecA allows the identification of methicillin-resistant Staphylococcus aureus (MRSA) strains by PCR amplification of a sequence covering the right junction of the H2O elements and the adjacent chromosomal region encoding the species-specific ORFX.