B
Brian O'Connell
Researcher at Trinity College, Dublin
Publications - 125
Citations - 5178
Brian O'Connell is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Submandibular gland & Salivary gland. The author has an hindex of 38, co-authored 119 publications receiving 4865 citations. Previous affiliations of Brian O'Connell include National Institutes of Health & University of Rochester.
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Journal ArticleDOI
Detection of Staphylococcal Cassette Chromosome mec Type XI Carrying Highly Divergent mecA, mecI, mecR1, blaZ, and ccr Genes in Human Clinical Isolates of Clonal Complex 130 Methicillin-Resistant Staphylococcus aureus
Anna C. Shore,E.C. Deasy,Peter Slickers,Gráinne I. Brennan,Brian O'Connell,Stefan Monecke,Ralf Ehricht,David C. Coleman +7 more
TL;DR: Two clonal complex 130 methicillin-resistant Staphylococcus aureus isolates from patients in Irish hospitals were identified that were phenotypically PBP 2a positive but lacked mecA by conventional PCR and by DNA microarray screening, suggesting they may have originated in another taxon.
Journal ArticleDOI
Trp1, a Candidate Protein for the Store-operated Ca2+Influx Mechanism in Salivary Gland Cells
Xibao Liu,Weiching Wang,Brij B. Singh,Timothy Lockwich,Julie Jadlowiec,Brian O'Connell,Robert B. Wellner,Michael X. Zhu,Indu S. Ambudkar +8 more
TL;DR: Aggregate data demonstrate an association between Trp1 and SOC and strongly suggest that Trp 1 is involved in this mechanism in HSG cells.
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Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands
Christine Delporte,Brian O'Connell,Xinjun He,Henry E. Lancaster,Anne C. O'Connell,Peter Agre,Bruce J. Baum +6 more
TL;DR: The results suggest that hAQP1 gene transfer may have potential as an unique approach for the treatment of postradiation salivary hypofunction.
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A Collagen-glycosaminoglycan Scaffold Supports Adult Rat Mesenchymal Stem Cell Differentiation Along Osteogenic and Chondrogenic Routes
Eric Farrell,Fergal J. O'Brien,Fergal J. O'Brien,Paul Doyle,Jan Fischer,Ionnais Yannas,Brendan A.C. Harley,Brian O'Connell,Patrick J. Prendergast,Veronica A. Campbell +9 more
TL;DR: It is demonstrated that adult rat mesenchymal stem cells can undergo osteogenesis when grown on the collagen-glycosaminoglycan scaffold and stimulated with osteogenic factors, as evaluated by the temporal induction of the bone-specific proteins, collagen I and osteocalcin, and subsequent matrix mineralization.
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Evaluation of Molecular Typing Methods in Characterizing a European Collection of Epidemic Methicillin-Resistant Staphylococcus aureus Strains: the HARMONY Collection
Barry Cookson,D. Ashley Robinson,Alastair B. Monk,Stephen Murchan,Ariane Deplano,Rafael De Ryck,Marc Struelens,Christina Scheel,Vivian Fussing,Saara Salmenlinna,Jaana Vuopio-Varkila,C Cuny,Wolfgang Witte,Panayotis T. Tassios,N. J. Legakis,Willem B. van Leeuwen,Alex van Belkum,A. Vindel,Javier Garaizar,Sara Hæggman,Barbro Olsson-Liljequist,Ulrika Ransjo,Manica Müller-Premru,Waleria Hryniewicz,Angela S. Rossney,Brian O'Connell,Benjamin R. D. Short,Jonathan C. Thomas,Simon J. O’Hanlon,Mark C. Enright +29 more
TL;DR: It is demonstrated that the integration of such technologies is achievable, although common protocols (such as those developed for PFGE) may also be important, as is the use of centralized Internet sites to facilitate data analysis.