D
D. Ashley Robinson
Researcher at University of Mississippi Medical Center
Publications - 73
Citations - 8676
D. Ashley Robinson is an academic researcher from University of Mississippi Medical Center. The author has contributed to research in topics: Population & SCCmec. The author has an hindex of 34, co-authored 73 publications receiving 8033 citations. Previous affiliations of D. Ashley Robinson include University of Bath & University of Mississippi.
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Journal ArticleDOI
The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA)
Mark C. Enright,D. Ashley Robinson,Gaynor Randle,Edward J. Feil,Hajo Grundmann,Brian G. Spratt +5 more
TL;DR: This work analyzes an international collection of 912 MRSA and methicillin-susceptible S. aureus isolates to establish the likely evolutionary origins of each major MRSA clone, the genotype of the original MRSAclone and its MSSA progenitor, and the extent of acquisition and horizontal movement of the methiillin resistance genes.
Journal ArticleDOI
Staphylococcus aureus CC398: Host Adaptation and Emergence of Methicillin Resistance in Livestock
Lance B. Price,Marc Stegger,Henrik Hasman,Maliha Aziz,Jesper Larsen,Paal Skytt Andersen,Talima Pearson,Andrew E. Waters,Jeffrey T. Foster,James M. Schupp,John D. Gillece,Elizabeth M. Driebe,Cindy M. Liu,Cindy M. Liu,Burkhard Springer,Irena Zdovc,Antonio Battisti,Alessia Franco,Jacek Żmudzki,Stefan Schwarz,Patrick Butaye,Eric Jouy,Constança Pomba,M. Concepción Porrero,Raymond Ruimy,Tara C. Smith,D. Ashley Robinson,J. Scott Weese,Carmen Sofia Arriola,Fangyou Yu,Frédéric Laurent,Paul Keim,Paul Keim,Robert Skov,Frank Møller Aarestrup +34 more
TL;DR: The results strongly suggest that livestock-associated MRSA CC398 originated in humans as MSSA, which appears to have undergone a rapid radiation in conjunction with the jump from humans to livestock, where it subsequently acquired tetracycline and methicillin resistance.
Journal ArticleDOI
How Clonal Is Staphylococcus aureus
Edward J. Feil,Jessica E. Cooper,Hajo Grundmann,D. Ashley Robinson,Mark C. Enright,Tony Berendt,Sharon J. Peacock,John Maynard Smith,Michael F. Murphy,Brian G. Spratt,Catrin E. Moore,Nicholas P. J. Day +11 more
TL;DR: Examination of the sequence changes at MLST loci during clonal diversification shows that point mutations give rise to new alleles at least 15-fold more frequently than does recombination, which suggests that homologous recombination does contribute toward the evolution of this species over the long term.
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Global Spread of Vancomycin-resistant Enterococcus faecium from Distinct Nosocomial Genetic Complex
Rob J. L. Willems,Janetta Top,Marga van Santen,D. Ashley Robinson,Teresa M. Coque,Fernando Baquero,Hajo Grundmann,Marc J. M. Bonten +7 more
TL;DR: Preventing further spread of this epidemic E. faecium subpopulation is critical, and efforts should focus on the early disclosure of ampicillin-resistant complex-17 strains.
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A Novel Staphylococcus aureus Biofilm Phenotype Mediated by the Fibronectin-Binding Proteins, FnBPA and FnBPB
Eoghan O'Neill,Eoghan O'Neill,Clarissa Pozzi,Patrick Houston,Hilary Humphreys,D. Ashley Robinson,Anthony Loughman,Timothy J. Foster,James P. O'Gara +8 more
TL;DR: It is reported that MRSA biofilm development was promoted under mildly acidic growth conditions triggered by the addition of glucose to the growth medium and identified a novel S. aureus biofilm phenotype promoted by FnBPA and FnBPB which is apparently independent of the known ligand-binding activities of these multifunctional surface proteins.