C
C. Shad Thaxton
Researcher at Northwestern University
Publications - 104
Citations - 10390
C. Shad Thaxton is an academic researcher from Northwestern University. The author has contributed to research in topics: Cancer & Colloidal gold. The author has an hindex of 36, co-authored 101 publications receiving 9704 citations. Previous affiliations of C. Shad Thaxton include International Institute of Minnesota.
Papers
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Journal ArticleDOI
Templated high density lipoprotein nanoparticles as potential therapies and for molecular delivery.
TL;DR: High density lipoproteins are dynamic natural nanoparticles best known for their role in cholesterol transport and the inverse correlation that exists between blood HDL levels and the risk of developing coronary heart disease.
Journal ArticleDOI
Multifunctional polymeric nanoparticles from diverse bioactive agents.
Paul A. Bertin,Julianne M. Gibbs,Clifton K.-F. Shen,C. Shad Thaxton,William A. Russin,Chad A. Mirkin,SonBinh T. Nguyen +6 more
TL;DR: A rational approach for assembling diverse bioactive agents, such as DNA, proteins, and drug molecules, into core-shell multifunctional polymeric nanoparticles (PNPs) that can be internalized in human breast cancer cells is presented.
Patent
Nucleic acid functionalized nanoparticles for therapeutic applications
TL;DR: In this paper, materials and methods for regulating gene expression using nanoparticles functionalized with antisense oligonucleotides are provided. But they do not address the problem of gene expression regulation.
Journal ArticleDOI
Nanoparticle Targeting and Cholesterol Flux Through Scavenger Receptor Type B-1 Inhibits Cellular Exosome Uptake.
Michael P. Plebanek,R. Kannan Mutharasan,Olga V. Volpert,Alexandre Matov,Alexandre Matov,Jesse C. Gatlin,C. Shad Thaxton +6 more
TL;DR: In this article, a synthetic nanoparticle mimic of HDL (HDL NP) that binds the scavenger receptor type B-1 (SR-B1) and removes cholesterol through this receptor would inhibit cellular exosome uptake.