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Camila Squarzoni Dale
Researcher at University of São Paulo
Publications - 51
Citations - 1650
Camila Squarzoni Dale is an academic researcher from University of São Paulo. The author has contributed to research in topics: Hyperalgesia & Neuropathic pain. The author has an hindex of 19, co-authored 46 publications receiving 1383 citations. Previous affiliations of Camila Squarzoni Dale include University of Toulouse & French Institute of Health and Medical Research.
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Journal ArticleDOI
Hemopressin is an inverse agonist of CB1 cannabinoid receptors.
Andrea S. Heimann,Ivone Gomes,Camila Squarzoni Dale,Rosana L. Pagano,Achla Gupta,Laura L. de Souza,Augusto Ducati Luchessi,Leandro M. Castro,Renata Giorgi,Vanessa Rioli,Emer S. Ferro,Lakshmi A. Devi +11 more
TL;DR: The identification of hemopressin (PVNFKFLSH) as a peptide ligand that selectively binds CB1 cannabinoid receptors is identified and it is found that it exhibits antinociceptive effects when administered by either intrathecal, intraplantar, or oral routes, underscoring hemopressingin's therapeutic potential.
Journal ArticleDOI
Differential role of N-type calcium channel splice isoforms in pain.
Christophe Altier,Camila Squarzoni Dale,Alexandra E. Kisilevsky,Kevin Chapman,Andrew J. Castiglioni,Elizabeth A. Matthews,Rhian M. Evans,Anthony H. Dickenson,Diane Lipscombe,Nathalie Vergnolle,Gerald W. Zamponi +10 more
TL;DR: Splice isoform-specific small interfering RNA silencing in vivo reveals that channels containing exon 37a are specifically required for mediating basal thermal nociception and for developing thermal and mechanical hyperalgesia during inflammatory and neuropathic pain.
Journal ArticleDOI
Motor cortex stimulation inhibits thalamic sensory neurons and enhances activity of PAG neurons: Possible pathways for antinociception
Rosana L. Pagano,Erich Talamoni Fonoff,Camila Squarzoni Dale,Gerson Ballester,Manoel Jacobsen Teixeira,Luiz R.G. Britto +5 more
TL;DR: The present findings suggest that inhibition of thalamic sensory neurons and disinhibition of the neurons in periaqueductal gray are at least in part responsible for the motor cortex stimulation‐induced antinociception.
Journal ArticleDOI
Hemoglobin-derived Peptides as Novel Type of Bioactive Signaling Molecules
Ivone Gomes,Camila Squarzoni Dale,Kimbie Casten,Miriam A. Geigner,Fabio C. Gozzo,Emer S. Ferro,Andrea S. Heimann,Lakshmi A. Devi +7 more
TL;DR: The status of the HB peptide field is reviewed and recent reports on the identification of a molecular target for a novel set of Hb peptides, hemopressins, and the implication of these peptides to normal cell function and disease are highlighted.
Journal ArticleDOI
Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis.
Jean-Paul Motta,Jean-Paul Motta,Jean-Paul Motta,Laurent Magne,Laurent Magne,Delphyne Descamps,Delphyne Descamps,Corinne Rolland,Corinne Rolland,Corinne Rolland,Camila Squarzoni Dale,Camila Squarzoni Dale,Camila Squarzoni Dale,Perrine Rousset,Perrine Rousset,Perrine Rousset,Laurence Martin,Laurence Martin,Laurence Martin,Nicolas Cenac,Nicolas Cenac,Nicolas Cenac,Viviane Balloy,Viviane Balloy,Michel Huerre,Leopold F. Fröhlich,Dieter E. Jenne,Julien Wartelle,Azzaq Belaaouaj,Emmanuel Mas,Jean-Pierre Vinel,Laurent Alric,Michel Chignard,Michel Chignard,Nathalie Vergnolle,Nathalie Vergnolle,Nathalie Vergnolle,Jean-Michel Sallenave,Jean-Michel Sallenave +38 more
TL;DR: The role of elafin, a serine protease inhibitor expressed by skin and mucosal surfaces in human inflammatory conditions, and the proteases neutrophil elastase (NE) and proteinase-3 (PR-3) in mice with colitis was investigated in this paper.