Carine Beysen

TL;DR: The data suggest that dietary fructose specifically increases DNL, promotes dyslipidemia, decreases insulin sensitivity, and increases visceral adiposity in overweight/obese adults.

TL;DR: Dietary manipulation would be more readily achieved by the general population than the current recommendations and could result in considerable improvement in insulin sensitivity, reducing the risk of developing Type II diabetes.

TL;DR: 2H2O labeling permits sensitive, quantitative, operationally simple measurements of protein turnover in vivo by the rise-to-plateau approach, especially for proteins with slow constitutive turnover.

TL;DR: Oral administration of Compound 1 preferentially inhibited ACC enzymatic activity in the liver, reduced hepatic malonyl‐CoA levels, and enhanced hepatic ketogenesis, and these studies warrant further investigation into the therapeutic utility of liver‐directed ACC inhibition for the treatment of NAFLD and hepatic insulin resistance.

TL;DR: This study compared cholesterol and lipoprotein kinetics in patients with active RA with those in matched healthy volunteers to compare cholesterol and lipid metabolism associated with RA.