C
Claire E. Wainwright
Researcher at University of Queensland
Publications - 225
Citations - 10700
Claire E. Wainwright is an academic researcher from University of Queensland. The author has contributed to research in topics: Cystic fibrosis & Ivacaftor. The author has an hindex of 48, co-authored 204 publications receiving 9018 citations. Previous affiliations of Claire E. Wainwright include Exponent & University of California, San Diego.
Papers
More filters
Journal ArticleDOI
A CFTR potentiator in patients with cystic fibrosis and the G551D mutation
Bonnie W. Ramsey,Jane C. Davies,N. Gerard McElvaney,Elizabeth Tullis,Scott C. Bell,Pavel Dř evínek,Matthias Griese,Edward F. McKone,Claire E. Wainwright,Michael W. Konstan,Richard B. Moss,Felix Ratjen,Isabelle Sermet-Gaudelus,Steven M. Rowe,Qunming Dong,Sally Rodriguez,Karl Yen,Claudia L. Ordoñez,J. Stuart Elborn +18 more
TL;DR: Ivacaftor was associated with improvements in lung function at 2 weeks that were sustained through 48 weeks and substantial improvements were also observed in the risk of pulmonary exacerbations, patient-reported respiratory symptoms, weight, and concentration of sweat chloride.
Journal ArticleDOI
Efficacy and Safety of Ivacaftor in Patients Aged 6 to 11 Years with Cystic Fibrosis with a G551D Mutation
Jane C. Davies,Jane C. Davies,Claire E. Wainwright,Gerard J. Canny,Mark A. Chilvers,Michelle S. Howenstine,Anne Munck,Jochen G. Mainz,Sally Rodriguez,Haihong Li,Karl Yen,Claudia L. Ordoñez,Richard C. Ahrens +12 more
TL;DR: In patients who are younger and healthier than those in previously studied populations, ivacaftor demonstrated a significant improvement in pulmonary function, weight, and CFTR activity compared with placebo.
Journal ArticleDOI
Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium.
Josephine M. Bryant,Josephine M. Bryant,Dorothy M Grogono,Dorothy M Grogono,Daniela Rodriguez-Rincon,Isobel Everall,Karen Brown,Karen Brown,Pablo Moreno,Deepshikha Verma,Emily Hill,Judith Drijkoningen,Peter H. Gilligan,Charles R. Esther,Peadar G. Noone,Olivia Giddings,Scott C. Bell,Scott C. Bell,Rachel Thomson,Claire E. Wainwright,Claire E. Wainwright,Chris Coulter,Sushil Pandey,Michelle Wood,Michelle Wood,Rebecca E Stockwell,Rebecca E Stockwell,Kay A. Ramsay,Kay A. Ramsay,Laura J. Sherrard,Timothy J. Kidd,Timothy J. Kidd,Nassib Jabbour,Graham R. Johnson,Luke D. Knibbs,Lidia Morawska,Peter D. Sly,Andrew Jones,Diana Bilton,Ian F. Laurenson,Michael Ruddy,Stephen Bourke,Ian C. J. W. Bowler,Stephen J Chapman,Andrew Clayton,Mairi Cullen,Owen J. Dempsey,Miles Denton,M. Desai,Richard J Drew,Frank Edenborough,Jason T. Evans,Jonathan Folb,Thomas Daniels,Helen Humphrey,Barbara Isalska,Søren Jensen-Fangel,Bodil Jönsson,Andrew M Jones,Terese L. Katzenstein,Troels Lillebaek,Gordon MacGregor,Sarah Mayell,Michael Millar,Deborah E. Modha,Edward F. Nash,C. O'Brien,Deirdre O'Brien,Chandra Ohri,Caroline S. Pao,Daniel Peckham,Felicity Perrin,Audrey Perry,Tania Pressler,Laura Prtak,Tavs Qvist,Ali Robb,Helen Rodgers,Kirsten Schaffer,Nadia Shafi,Jakko van Ingen,Martin Walshaw,Danie Watson,Noreen West,Joanna L. Whitehouse,Charles S. Haworth,Simon R. Harris,Diane J. Ordway,Julian Parkhill,R. Andres Floto,R. Andres Floto +90 more
TL;DR: Using whole-genome analysis of a global collection of clinical isolates, it is shown that the majority of M. abscessus infections are acquired through transmission, potentially via fomites and aerosols, of recently emerged dominant circulating clones that have spread globally.
Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium
Josephine M. Bryant,Dorothy M Grogono,Daniela Rodriguez-Rincon,Isobel Everall,Karen Brown,Pablo Moreno,Deepshikha Verma,E. Hill,J. Drijkoningen,Peter H. Gilligan,Charles R. Esther,Peadar G. Noone,Olivia Giddings,Scott C. Bell,Rachel Thomson,Claire E. Wainwright,Chris Coulter,Sushil Pandey,Michelle Wood,Rebecca E Stockwell,Kay A. Ramsay,Laura J. Sherrard,Timothy J. Kidd,Nassib Jabbour,Graham R. Johnson,Luke D. Knibbs,Lidia Morawska,Peter D. Sly,Alison Jones,Diana Bilton,Ian F. Laurenson,Michael Ruddy,Stephen Bourke,Ian C. J. W. Bowler,Stephen J Chapman,Andrew Clayton,M. Cullen,Owen J. Dempsey,Miles Denton,M. Desai,R. J. Drew,F. Edenborough,Jason T. Evans,Jonathan Folb,T. Daniels,H. Humphrey,B. Isalska,Søren Jensen-Fangel,Bodil Jönsson,Andrew Jones,Terese L. Katzenstein,Troels Lillebaek,Gordon MacGregor,S. Mayell,Michael Millar,Deborah E. Modha,Edward F. Nash,C. O'Brien,D. OBrien,Chandra Ohri,Caroline S. Pao,Daniel Peckham,Felicity Perrin,Audrey Perry,Tacjana Pressler,L. Prtak,Tavs Qvist,A. Robb,Helen Rodgers,K. Schaffer,Nadia Shafi,J. van Ingen,M. Walshaw,D. Watson,Noreen West,Joanna L. Whitehouse,Charles S. Haworth,Simon R. Harris,Diane J. Ordway,Julian Parkhill,R.A. Floto +80 more
TL;DR: In this paper, the authors used whole-genome analysis of a global collection of clinical isolates to show that the majority of M. abscessus infections are acquired through transmission, potentially via fomites and aerosols, of recently emerged dominant circulating clones.
Journal ArticleDOI
Nebulised hypertonic saline solution for acute bronchiolitis in infants
TL;DR: Current evidence suggests nebulised 3% saline may significantly reduce the length of hospital stay among infants hospitalised with non-severe acute viral bronchiolitis and improve the clinical severity score in both outpatient and inpatient populations.