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Carmen V. Ozuna

Researcher at Spanish National Research Council

Publications -  13
Citations -  978

Carmen V. Ozuna is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Gluten & Epitope. The author has an hindex of 8, co-authored 12 publications receiving 697 citations.

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Low-gluten, nontransgenic wheat engineered with CRISPR/Cas9.

TL;DR: The low‐gluten, transgene‐free wheat lines described here could be used to produce low-gluten foodstuff and serve as source material to introgress this trait into elite wheat varieties.
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High-efficiency gene targeting in hexaploid wheat using DNA replicons and CRISPR/Cas9.

TL;DR: High frequencies of GT using WDV-based DNA replicons will make it possible to edit complex cereal genomes without the need to integrate GT reagents into the genome.
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Targeting of prolamins by RNAi in bread wheat: effectiveness of seven silencing‐fragment combinations for obtaining lines devoid of coeliac disease epitopes from highly immunogenic gliadins

TL;DR: The effectiveness of seven plasmid combinations, encompassing RNAi fragments from α-, γ-, ω-gliadins, and LMW glutenin subunits, for silencing the expression of different prolamin fractions are reported, raising the prospect of breeding wheat species with low levels of harmful gluten, and of achieving the important goal of developing nontoxic wheat cultivars.
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Diversification of the celiac disease α‐gliadin complex in wheat: a 33‐mer peptide with six overlapping epitopes, evolved following polyploidization

TL;DR: These findings are important for reducing the incidence of CD by the breeding/selection of wheat varieties with low stimulatory capacity of T cells and advanced genome-editing techniques (TALENs, CRISPR) will be easier to implement on the small group of α-gliadins containing only immunogenic peptides.