Measuring normal and pathological anxiety-like behaviour in mice: a review.
Catherine Belzung,Guy Griebel +1 more
TLDR
When assessing the behaviour of mice, it is necessary to increase the range of behavioural paradigms used, including animal models of "state" and "trait" anxiety.About:
This article is published in Behavioural Brain Research.The article was published on 2001-11-08 and is currently open access. It has received 870 citations till now. The article focuses on the topics: Anxiety & Elevated plus maze.read more
Citations
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The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review
Laëtitia Prut,Catherine Belzung +1 more
TL;DR: Compounds that have a different spectrum of therapeutic efficacy in anxiety disorders such as panic attacks, generalized anxiety disorder or obsessive-compulsive disorder were poorly effective as anxiolytics in the open field test, suggesting that this paradigm may not model features of anxiety disorders.
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The use of the elevated plus maze as an assay of anxiety-related behavior in rodents
Alicia A. Walf,Cheryl A. Frye +1 more
TL;DR: The elevated plus maze is a widely used behavioral assay for rodents and it has been validated to assess the anti-anxiety effects of pharmacological agents and steroid hormones, and to define brain regions and mechanisms underlying anxiety-related behavior.
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The mouse light/dark box test.
Michel Bourin,Martine Hascoët +1 more
TL;DR: The light/dark test may be useful to predict anxiolytic-like or anxiogenic-like activity in mice, and has the advantages of being quick and easy to use, without requiring the prior training of animals.
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The ascent of mouse: advances in modelling human depression and anxiety.
TL;DR: The current status of research into developing appropriate tests for assessing depression- and anxiety-related behaviours in mice is assessed.
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The neurobiology and control of anxious states
TL;DR: The present article focuses in particular upon the multifarious and complex roles of individual modulators, often as a function of the specific receptor type and neuronal substrate involved in their actions; novel targets for the management of anxiety disorders; the influence of neurotransmitters and other agents upon performance in the VCT; data acquired from complementary pharmacological and genetic strategies and, finally, several open questions likely to orientate future experimental- and clinical-research.
References
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DSM-IV: Diagnostic and Statistical Manual of Mental Disorders
TL;DR: The DSM-IV: Diagnostic and Statistical Manual of Mental Disorders , fourth edition, was developed with a great deal of input from mental health professionals and professional organizations and is a great improvement over thethird edition (DSM-III) and the third edition, revised (DSS-III-R).
Journal ArticleDOI
The use of a plus-maze to measure anxiety in the mouse
TL;DR: The plus-maze appears to be a useful test with which to investigate both anxiolytic and anxiogenic agents.
Book
Contingencies of reinforcement : a theoretical analysis
TL;DR: In this case, more books you read more knowledge you know, but it can mean also the bore is full as mentioned in this paper. But this is some of how reading will give you the kindness.
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Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat
Christian Caldji,Beth Tannenbaum,Shakti Sharma,Darlene D. Francis,Paul M. Plotsky,Michael J. Meaney +5 more
TL;DR: It is suggested that maternal care during infancy serves to "program" behavioral responses to stress in the offspring by altering the development of the neural systems that mediate fearfulness.
Related Papers (5)
The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review
Laëtitia Prut,Catherine Belzung +1 more