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Showing papers by "Catherine Hambly published in 2018"


Journal ArticleDOI
TL;DR: In this article, the impact of Ramadan fasting on resting metabolic rate (RMR), activity, and total energy expenditure (TEE) was investigated in a study with healthy nonobese volunteers.

54 citations


Journal ArticleDOI
12 Dec 2018-BMJ
TL;DR: Very high dietary energy content of both full service and fast food restaurant meals is a widespread phenomenon that is probably supporting global obesity and provides a valid intervention target.
Abstract: Objective To measure the energy content of frequently ordered meals from full service and fast food restaurants in five countries and compare values with US data. Design Cross sectional survey. Setting 223 meals from 111 randomly selected full service and fast food restaurants serving popular cuisines in Brazil, China, Finland, Ghana, and India were the primary sampling unit; 10 meals from five worksite canteens were also studied in Finland. The observational unit was frequently ordered meals in selected restaurants. Main outcome measure Meal energy content, measured by bomb calorimetry. Results Compared with the US, weighted mean energy of restaurant meals was lower only in China (719 (95% confidence interval 646 to 799) kcal versus 1088 (1002 to 1181) kcal; P Conclusion Very high dietary energy content of both full service and fast food restaurant meals is a widespread phenomenon that is probably supporting global obesity and provides a valid intervention target.

37 citations


Journal ArticleDOI
01 Jan 2018-Obesity
TL;DR: The objective of this study was to measure body composition and examine the relationship between adiposity and cyclicity status, mediated by glucose, insulin, leptin, and inflammation.
Abstract: Funded by Eppley Foundation for Research . Grant Number: P30DK056336 Diabetes Research Center . Grant Number: P30DK079626 Nathan Shock Center on Aging . Grant Number: P30AG050886 National Heart, Lung, and Blood Institute . Grant Number: T32HL105349 Nutrition Obesity Research Center, University of Alabama, Birmingham

14 citations


Journal ArticleDOI
TL;DR: Raising offspring in golden hamsters comes at the cost of producing large amounts of body heat up to a level constraining energy intake, similar to that observed in some laboratory mice.
Abstract: Golden hamster females have the shortest known gestation period among placental mammals and at the same time raise very large litters of up to 16 offspring, which are born in a naked and blind state and are able to pick up food from days 12-14 only. We quantified energy metabolism and milk production in female golden hamsters raising offspring under cold (8°C), normal (22°C) and hot (30°C) ambient temperature conditions. We monitored energy intake, subcutaneous body temperature, daily energy expenditure, litter size and pup masses over the course of lactation. Our results show that, in line with the concept of heat dissipation limitation, female golden hamsters had the largest energy intake under the coldest conditions and a significantly lower intake at 30° (partial for influence of ambient temperature: F 2,403 =5.6; p= 0.004). Metabolisable energy intake as well as milk energy output showed the same pattern and were significantly different between the temperatures (partial for milk energy production: F 1,40 = 86.4; p 1,813 = 36.77; p

8 citations


Journal ArticleDOI
TL;DR: Data from this paper indicate that there may be a ‘soft’ limit dependent on female ‘choice’ on energy allocation to their litters, rather than a ’hard’, unbreachable limit defined by aspects of maternal physiology as is commonly assumed.
Abstract: Osei Duah Agemang was supported by a scholarship from the Cape University, Ghana. Lobke Maria Vaanholt was supported by a Rubicon grant from the Netherlands Organisation for Scientific Research (NWO).

7 citations


Journal ArticleDOI
TL;DR: Mice fed high-fat diets have reduced specific dynamic action and show improved reproductive performance, in agreement with predictions from the heat dissipation limitations theory.
Abstract: Maximal animal performance may be limited by the ability of an animal to dissipate heat: the heat dissipation limitation (HDL) theory. Because the incidental heat produced during digestion [specific dynamic action (SDA)] varies among diets, the HDL theory predicts that lactating female mice consuming diets with lower SDA should have increased reproductive performance. Dietary fat has a lower SDA than dietary carbohydrate. Female mice were fed low (LF), medium (MF) or high (HF) fat diets (10, 45 and 60% energy from fat, respectively) from days 4–18 of lactation. HF- and MF-fed mice weaned significantly heavier litters than LF mice. This was because they not only consumed more energy [metabolisable energy intake (Emei); HF: 306.5±25.0, MF: 340.5±13.5 kJ day−1] at peak lactation, but also delivered more milk energy to their pups [milk energy output (Emilk); HF: 203.2±49.9, MF 229.3±42.2 kJ day−1] than the LF-fed mice (Emei=266.7±4.5, Emilk=164.60±30.59 kJ day−1). A mathematical model based on the predictions from the HDL theory showed that this effect was greater than predicted from differences in SDA between the diets. Fatty acid profiles of the diets, milk and pups showed significant correlations between the profiles. Besides reduced SDA, HF- and MF-fed mice were probably able to directly transfer absorbed dietary fat into milk, reducing the heat production of lactogenesis and enabling them to perform better than expected from the HDL model. In summary, HF and MF diets had beneficial effects on reproductive performance compared with the LF diet because they enabled mice to generate milk more efficiently with less incidental heat production.

6 citations


Journal ArticleDOI
TL;DR: The large discrepancy between TEE and TEI suggests significant under reporting of dietary intake, suggesting that conventional sport-specific nutritional recommendations do not appear applicable.
Abstract: To formulate individualized dietary strategies for jockeys, it is vital that energy requirements are quantified. We measured total energy expenditure (TEE) over two separate weeks in spring and summer using doubly labelled water in a group of male flat jockeys (n = 8, 36.9 ± 5.7 years, 164 ± 8 cm, 54.6 ± 2.5 kg). Total energy intake (TEI) was self-recorded, as were all riding and structured exercise activity. Mean daily TEE was 10.83 (±2.3) and 10.66 (±1.76) MJ, (p = .61) respectively. Self-reported TEI were 6.03 (±1.7) and 5.37 (±1.1) MJ (p = .40), respectively, and were significantly lower than TEE (p = .01). Mean race rides were 17 (±6) and 13 (±3; p = 0.37) and horses ridden at morning exercise were 8 (±6) and 7 (±4; p = .77) respectively. Additional structured exercise was 76.25 (±95.1) and 52.5 (±80.9) min per week (p = .35), respectively. At the individual level, TEE was related to body mass and the level of non-racing physical activity, but not riding. Physical activity levels for TEE were 1.76 (±0.37) and 1.69 (±0.27; p = .59) and appear modest when compared with other athletes, and similar to age-matched non-athletes, suggesting that conventional sport-specific nutritional recommendations do not appear applicable. The large discrepancy between TEE and TEI suggests significant under reporting of dietary intake. These data now provide an appropriate framework from which to formulate jockey nutritional guidelines to promote the ability to achieve the daily weight target and improve athlete welfare.

6 citations


Journal ArticleDOI
01 Mar 2018-Obesity
TL;DR: In this paper, individual variations in ratings of physical attractiveness were broadly unrelated to rater BMI and suggest that mutual attraction is an unlikely explanation for assortative mating for obesity, which may explain why people who have high adiposity find other people with obesity more physically attractive than lean people.
Abstract: Objective Assortative mating for adiposity increases the genetic burden on offspring, but its causes remain unclear. One hypothesis is that people who have high adiposity find other people with obesity more physically attractive than lean people. Methods The attractiveness of sets of images of males and females who varied in adiposity were rated by opposite sex subjects (559 males and 340 females) across 12 countries. Results There was tremendous individual variability in attractiveness ratings. For female attractiveness, most males favored the leanest subjects, but others favored intermediate fatness, some were indifferent to body composition, and others rated the subjects with obesity as most attractive. For male images rated by females, the patterns were more complex. Most females favored subjects with low levels of adiposity (but not the lowest level), whereas others were indifferent to body fatness or rated the images depicting individuals with obesity as the most attractive. These patterns were unrelated to rater BMI. Among Caucasian males who rated the images of the thinnest females as being more attractive, the magnitude of the effect depended on rater BMI, indicating limited "mutual attraction." Conclusions Individual variations in ratings of physical attractiveness were broadly unrelated to rater BMI and suggest that mutual attraction is an unlikely explanation for assortative mating for obesity.

4 citations