Chao Xie

TL;DR: DIAMOND is introduced, an open-source algorithm based on double indexing that is 20,000 times faster than BLASTX on short reads and has a similar degree of sensitivity.

TL;DR: The results show that the number of reads, not the length of the reads is the key factor determining the resolution of detection, which favors the next-generation sequencing methods that rapidly produce large amount of short reads.

TL;DR: The conversion of floccular biomass to highly structured granules was found to be non-random, but strongly and positively correlated with N-acyl-homoserine-lactone (AHL)-mediated QS, and low concentrations of AHLs quantified in this study were sufficient to activate AHL bioreporters in situ in complex granular communities.

TL;DR: This work reports on the sequencing of 10,545 human genomes at 30×–40× coverage with an emphasis on quality metrics and novel variant and sequence discovery and concludes that high-coverage genome sequencing provides accurate detail on human variation for discovery and clinical applications.

TL;DR: Findings suggest that community-level interactions, such as sharing of public goods, are unique to the structured biofilm community, where the members are closely associated with each other.