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Chien-Feng Li
Researcher at National Health Research Institutes
Publications - 218
Citations - 4509
Chien-Feng Li is an academic researcher from National Health Research Institutes. The author has contributed to research in topics: Cancer & Nasopharyngeal carcinoma. The author has an hindex of 34, co-authored 191 publications receiving 3636 citations. Previous affiliations of Chien-Feng Li include Chung Hwa University of Medical Technology & Kaohsiung Medical University.
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Journal ArticleDOI
Deduction of Novel Genes Potentially Involved in Upper Tract Urothelial Carcinoma Using Next-Generation Sequencing and Bioinformatics Approaches
Hsiang-Ying Lee,Yi Jen Chen,Ching Chia Li,Wei-Ming Li,Ya Ling Hsu,Hsin Chih Yeh,Hung Lung Ke,Chun Nung Huang,Chien-Feng Li,Wen-Jeng Wu,Po-Lin Kuo,Po-Lin Kuo +11 more
TL;DR: The findings suggested novel miRNA target with SLIT3 regulation exerts potential prognostic value in UTUC, and future investigation is necessary to explore the role ofSLIT3 in the tumor development and progression of UTUC.
Journal ArticleDOI
O6-methylguanine-DNA methyltransferase modulates cisplatin-induced DNA double-strand breaks by targeting the homologous recombination pathway in nasopharyngeal carcinoma
Shang-Hung Chen,Shang-Hung Chen,Wen-Tsung Huang,Wan-Chen Kao,Sheng-Yen Hsiao,Hsin-Yi Pan,Chin-Wen Fang,Yow-Ling Shiue,Chia-Lin Chou,Chien-Feng Li,Chien-Feng Li +10 more
TL;DR: In this paper, the authors explored the interactions between MGMT and the homologous recombination (HR) pathway in CDDP-activated DDR and their clinical implications in nasopharyngeal carcinoma (NPC).
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Disruption of the pentraxin 3/CD44 interaction as an efficient therapy for triple‐negative breast cancers
Yu Wei Hsiao,Jhih-Ying Chi,Chien-Feng Li,Lei-Yi Chen,Yi Ting Chen,Hsin-Yin Liang,Yu Chih Lo,Jhen Yi Hong,Chin-Pin Chuu,Liang Yi Hung,Jyun Yi Du,Wenrui Chang,Ju-Ming Wang. +12 more
TL;DR: Two types of PTX3 inhibitors were developed and they showed a significant effect on attenuating growth and restricting the metastasis/invasion of MDA‐MB‐231 cells, suggesting that targeting thePTX3/CD44 interaction could be a new strategy for future TNBC therapies.
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Adult NTRK-rearranged spindle cell neoplasms of the viscera: with an emphasis on rare locations and heterologous elements
Jen-Wei Tsai,Jen-Chieh Lee,Tsung-Han S. Hsieh,Shi Huang,Pei Hang Lee,Ting-Tsan Liu,Yu Chien Kao,Ching-Di Chang,Tefu Weng,Chien-Feng Li,Jung-Chia Lin,Cher-Wei Liang,Yu Li Su,Ian Yi-Feng Chang,Yu-Ting Wang,Nien-Yi Chang,Shih Chen Yu,Jui-Chu Wang,Hsuan-Ying Huang +18 more
TL;DR: In this paper , the authors characterized visceral mesenchymal tumors harboring TPM3-NTRK1 with unknown fusion partner (colon/mesocolon) with RNA sequencing, FISH, RT-PCR, and immunohistochemistry.
Journal ArticleDOI
DDR2 overexpression in urothelial carcinoma indicates an unfavorable prognosis: a large cohort study.
Meng Chen Tsai,Wei-Ming Li,Chun Nung Huang,Hung Lung Ke,Ching Chia Li,Hsin Chih Yeh,Ti Chun Chan,Peir In Liang,Bi Wen Yeh,Wen-Jeng Wu,Sher Wei Lim,Chien-Feng Li +11 more
TL;DR: In vitro study revealed knockdown of DDR2 resulted in a depletion of cellular viability, migratory, and invasive ability, supporting the oncogenic function of DDR1 and helping to explain the poor prognosis of urothelial carcinoma.