C
Chien-Feng Li
Researcher at National Health Research Institutes
Publications - 218
Citations - 4509
Chien-Feng Li is an academic researcher from National Health Research Institutes. The author has contributed to research in topics: Cancer & Nasopharyngeal carcinoma. The author has an hindex of 34, co-authored 191 publications receiving 3636 citations. Previous affiliations of Chien-Feng Li include Chung Hwa University of Medical Technology & Kaohsiung Medical University.
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Journal ArticleDOI
CEBPD Reverses RB/E2F1-Mediated Gene Repression and Participates in HMDB-Induced Apoptosis of Cancer Cells
Yen-Chun Pan,Chien-Feng Li,Chiung-Yuan Ko,Min-Hsiung Pan,Pei-Jung Chen,Joseph T. Tseng,Wen-Chun Wu,Wen Chang Chang,Wen Chang Chang,A-Mei Huang,Esta Sterneck,Ju Ming Wang,Ju Ming Wang +12 more
TL;DR: It is demonstrated that HMDB kills cancer cells through activation of CEBPD pathways and suggest that HM DB can serve as a superior chemotherapeutic agent with limited potential for adverse side effects.
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Inhibition of the EGFR/STAT3/CEBPD Axis Reverses Cisplatin Cross-resistance with Paclitaxel in the Urothelial Carcinoma of the Urinary Bladder
Wei Jan Wang,Chien-Feng Li,Yu Yi Chu,Yu Hui Wang,Tzyh-Chyuan Hour,Chia Jui Yen,Wen Chang Chang,Wen Chang Chang,Ju Ming Wang +8 more
TL;DR: The results revealed the risk of CEBPD activation in CDDP-resistant UCUB cells and suggested a therapeutic strategy for patients with UCUB or UCUB resisted to CDDP and paclitaxel by combination with either gefitinib or S3I-201.
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Overexpression of a chromatin remodeling factor, RSF-1/HBXAP, correlates with aggressive oral squamous cell carcinoma.
Fu-Min Fang,Chien-Feng Li,Hsuan-Ying Huang,Ming-Tsong Lai,Chih-Mei Chen,I-Wen Chiu,Tian Li Wang,Fuu Jen Tsai,Ie Ming Shih,Jim Jinn-Chyuan Sheu +9 more
TL;DR: The results suggest that RSf-1 up-regulation is associated with several clinicopathological features of disease aggressiveness in OSCC patients, and RSF-1 plays an important role in maintaining cellular growth and survival in OS CC.
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Metabolic stress-induced phosphorylation of kap1 ser473 blocks mitochondrial fusion in breast cancer cells
Chun Ting Cheng,Ching Ying Kuo,Ching Ouyang,Chien-Feng Li,Yiyin Chung,David C. Chan,Hsing Jien Kung,David K. Ann +7 more
TL;DR: It is suggested that KAP1 Ser473 phosphorylation acts through MFN2 reduction to restrict mitochondrial hyperfusion, thereby contributing to cancer cell survival under conditions of sustained metabolic stress.
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Fibronectin overexpression is associated with latent membrane protein 1 expression and has independent prognostic value for nasopharyngeal carcinoma.
Li-Jung Ma,Sung-Wei Lee,Li-Ching Lin,Tzu-Ju Chen,I-Wei Chang,Han-Ping Hsu,Kwang-Yu Chang,Hsuan-Ying Huang,Chien-Feng Li,Chien-Feng Li +9 more
TL;DR: Fructose is upregulated in a subset of NPCs, and its increased immunoexpression significantly correlated with advanced features, justifying the potentiality of fibronectin as a theragnostic biomaker of NPC.