C
Chien-Feng Li
Researcher at National Health Research Institutes
Publications - 218
Citations - 4509
Chien-Feng Li is an academic researcher from National Health Research Institutes. The author has contributed to research in topics: Cancer & Nasopharyngeal carcinoma. The author has an hindex of 34, co-authored 191 publications receiving 3636 citations. Previous affiliations of Chien-Feng Li include Chung Hwa University of Medical Technology & Kaohsiung Medical University.
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Journal ArticleDOI
Cyclin-dependent kinase 4 overexpression is mostly independent of gene amplification and constitutes an independent prognosticator for nasopharyngeal carcinoma
TL;DR: CDK4 overexpression is mostly independent with gene amplification and represents a potential prognostic biomarker in NPC and may indicate tumor aggressiveness through cell cycle dysregulation.
Journal ArticleDOI
Glutamate Decarboxylase 1 Overexpression as a Poor Prognostic Factor in Patients with Nasopharyngeal Carcinoma.
Yi-Ying Lee,Tung-Bo Chao,Ming-Jen Sheu,Yu-Feng Tian,Tzu-Ju Chen,Sung-Wei Lee,Hong-Lin He,I-Wei Chang,Chung-Hsi Hsing,Ching-Yih Lin,Chien-Feng Li +10 more
TL;DR: The data reveal that GAD1 overexpression was correlated with advanced disease status and may thus be a critical prognostic indicator of poor outcomes in NPC and a potential therapeutic target to facilitate the development of effective treatment modalities.
Journal ArticleDOI
Amplification-driven BCL6-suppressed cytostasis is mediated by transrepression of FOXO3 and post-translational modifications of FOXO3 in urinary bladder urothelial carcinoma
Wen-Ren Wu,Jen-Tai Lin,Cheng-Tang Pan,Ti-Chun Chan,Chen-Liang Liu,Wen-Jeng Wu,Jim Jinn-Chyuan Sheu,Bi-Wen Yeh,Steven Kuan-Hua Huang,Jheng-Yan Jhung,Meng-Shin Hsiao,Chien-Feng Li,Yow-Ling Shiue +12 more
TL;DR: In vivo and in vitro studies suggested that BCL6 serves a poor prognostic factor in UBUC patients and functions as an oncogene through direct transrepression of the FOXO3 gene, downregulation and phosphorylation of the FoxO3 protein.
Journal ArticleDOI
Downregulation of the cytochrome P450 4B1 protein confers a poor prognostic factor in patients with urothelial carcinomas of upper urinary tracts and urinary bladder.
Jen-Tai Lin,Ti-Chun Chan,Chien-Feng Li,Steven K.H. Huan,Yu-Feng Tian,Peir-In Liang,Cheng-Tang Pan,Cheng-Tang Pan,Yow-Ling Shiue,Yow-Ling Shiue +9 more
TL;DR: The findings showed that downregulation of CYP4B1 protein level is an independent unfavorable prognosticator and loss of the CYP 4B1 gene expression may play an important role in UC progression.
Journal ArticleDOI
Is preoperative anemia a risk factor for upper tract urothelial carcinoma following radical nephroureterectomy
Hsin Chih Yeh,Tsu Ming Chien,Wen-Jeng Wu,Ching Chia Li,Wei-Ming Li,Hung Lung Ke,Yii Her Chou,Chii Jye Wang,Shu Pin Huang,Chien-Feng Li,Chien-Feng Li,Peir In Liang,Chun Nung Huang +12 more
TL;DR: Among patients without stage 5 CKD, preoperative anemia was a significant prognostic factor to predict metastatic progression and cancer-specific death in UTUC following radical nephroureterectomy.