C
Chongle Pan
Researcher at University of Oklahoma
Publications - 95
Citations - 4301
Chongle Pan is an academic researcher from University of Oklahoma. The author has contributed to research in topics: Medicine & Gene. The author has an hindex of 34, co-authored 80 publications receiving 3715 citations. Previous affiliations of Chongle Pan include United States Department of Energy & University of Tennessee.
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Journal ArticleDOI
Integrated Metagenomics/Metaproteomics Reveals Human Host-Microbiota Signatures of Crohn's Disease
Alison R. Erickson,Brandi L. Cantarel,Regina Lamendella,Youssef Darzi,Emmanuel F. Mongodin,Chongle Pan,Manesh Shah,Jonas Halfvarson,Curt Tysk,Bernard Henrissat,Jeroen Raes,Nathan C Verberkmoes,Claire M. Fraser,Robert L. Hettich,Janet K. Jansson +14 more
TL;DR: The eco-systems biology approach underscores the link between the gut microbiota and functional alterations in the pathophysiology of Crohn's disease and aids in identification of novel diagnostic targets and disease specific biomarkers.
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Systematic Comparison of Label-Free, Metabolic Labeling, and Isobaric Chemical Labeling for Quantitative Proteomics on LTQ Orbitrap Velos
TL;DR: The results show that the spectral counting method provides the deepest proteome coverage for identification, but its quantification performance is worse than labeling-based approaches, especially the quantification reproducibility.
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Effects of Diet on Resource Utilization by a Model Human Gut Microbiota Containing Bacteroides cellulosilyticus WH2, a Symbiont with an Extensive Glycobiome
Nathan P. McNulty,Meng Wu,Alison R. Erickson,Chongle Pan,Brian K. Erickson,Eric C. Martens,Nicholas A. Pudlo,Brian D. Muegge,Bernard Henrissat,Robert L. Hettich,Jeffrey I. Gordon +10 more
TL;DR: Artificial human gut microbial communities implanted into germ-free mice provide insights into how species-level responses to changes in diet give rise to community-level structural and functional reconfiguration and how types of bacteria prioritize use of available nutrients in vivo.
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Impact of Pretreated Switchgrass and Biomass Carbohydrates on Clostridium thermocellum ATCC 27405 Cellulosome Composition: A Quantitative Proteomic Analysis
Babu Raman,Chongle Pan,Gregory B. Hurst,Miguel Rodriguez,Catherine K. McKeown,Patricia K. Lankford,Nagiza F. Samatova,Nagiza F. Samatova,Jonathan R. Mielenz +8 more
TL;DR: Overall, the quantitative results suggest a coordinated substrate-specific regulation of cellulosomal subunit composition in C. thermocellum to better suit the organism's needs for growth under different conditions.
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Efficient and specific trypsin digestion of microgram to nanogram quantities of proteins in organic-aqueous solvent systems.
TL;DR: This report is the first using mass spectrometry data to show a linkage between digestion solvent and trypsin specificity, resulting in smaller numbers of semitryptic peptides than an overnight digestion protocol using an aqueous solvent.