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Eric C. Martens
Researcher at University of Michigan
Publications - 132
Citations - 16549
Eric C. Martens is an academic researcher from University of Michigan. The author has contributed to research in topics: Bacteroides thetaiotaomicron & Microbiome. The author has an hindex of 46, co-authored 111 publications receiving 12067 citations. Previous affiliations of Eric C. Martens include Washington University in St. Louis.
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Journal ArticleDOI
A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility
Mahesh Desai,Mahesh Desai,Anna M. Seekatz,Nicole M. Koropatkin,Nobuhiko Kamada,Christina A. Hickey,Mathis Wolter,Nicholas A. Pudlo,Sho Kitamoto,Nicolas Terrapon,Arnaud Muller,Vincent B. Young,Bernard Henrissat,Paul Wilmes,Thaddeus S. Stappenbeck,Gabriel Núñez,Eric C. Martens +16 more
TL;DR: Dietary fiber deprivation, together with a fiber-deprived, mucus-eroding microbiota, promotes greater epithelial access and lethal colitis by the mucosal pathogen, Citrobacter rodentium.
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How glycan metabolism shapes the human gut microbiota
TL;DR: How glycans shape the composition of the gut microbiota over various periods of time is described, the mechanisms by which individual microorganisms degrade these glycans, and potential opportunities to intentionally influence this ecosystem for better health and nutrition are described.
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Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella
Petia Kovatcheva-Datchary,Anne Nilsson,Rozita Akrami,Ying Shiuan Lee,Filipe De Vadder,Tulika Arora,Anna Hallén,Eric C. Martens,Inger Björck,Fredrik Bäckhed,Fredrik Bäckhed +10 more
TL;DR: It is indicated that Prevotella plays a role in the BKB-induced improvement in glucose metabolism observed in certain individuals, potentially by promoting increased glycogen storage.
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Mucosal Glycan Foraging Enhances Fitness and Transmission of a Saccharolytic Human Gut Bacterial Symbiont
TL;DR: PUL-mediated glycan catabolism is an important component in gut colonization and may impact microbiota ecology, and the mechanisms underlying host glycan foraging in vivo and in vitro are defined.
Journal ArticleDOI
Recognition and degradation of plant cell wall polysaccharides by two human gut symbionts.
Eric C. Martens,Eric C. Martens,Elisabeth C. Lowe,Herbert C. Chiang,Nicholas A. Pudlo,Meng-Meng Wu,Nathan P. McNulty,D. Wade Abbott,Bernard Henrissat,Harry J. Gilbert,Harry J. Gilbert,David N. Bolam,Jeffrey I. Gordon +12 more
TL;DR: Competition for nutrients contained in diverse types of plant cell wall-associated polysaccharides may explain the evolution of substrate-specific catabolic gene modules in common bacterial members of the human gut microbiota.