C
Choon Jin Ooi
Researcher at Singapore General Hospital
Publications - 31
Citations - 2357
Choon Jin Ooi is an academic researcher from Singapore General Hospital. The author has contributed to research in topics: Inflammatory bowel disease & Ulcerative colitis. The author has an hindex of 14, co-authored 29 publications receiving 1954 citations. Previous affiliations of Choon Jin Ooi include Harvard University & National University of Singapore.
Papers
More filters
Journal ArticleDOI
Incidence and phenotype of inflammatory bowel disease based on results from the Asia-pacific Crohn's and colitis epidemiology study.
Siew C. Ng,Whitney Tang,Jessica Y.L. Ching,May Wong,Chung Mo Chow,Aric J. Hui,Tc Wong,Vincent K S Leung,Steve Tsang,Hon Ho Yu,Mo Fong Li,Ka Kei Ng,Michael A. Kamm,Corrie Studd,Sally Bell,Rupert W. Leong,H. Janaka de Silva,Anuradhani Kasturiratne,M.N.F. Mufeena,Khoon Lin Ling,Choon Jin Ooi,Poh Seng Tan,David E. Ong,Khean L. Goh,Ida Hilmi,Pises Pisespongsa,Sathaporn Manatsathit,Rungsun Rerknimitr,Satimai Aniwan,Yu-Fang Wang,Qin Ouyang,Zhirong Zeng,Zhenhua Zhu,Min Hu Chen,Pin Jin Hu,Kaichun Wu,Xin Wang,Marcellus Simadibrata,Murdani Abdullah,Justin C.Y. Wu,Joseph J.Y. Sung,Francis K.L. Chan +41 more
TL;DR: The Asia-Pacific Crohn's and Colitis Epidemiology Study as discussed by the authors was a large-scale population-based study and found that although the incidence of IBD varies throughout Asia, it is still lower than in the West.
Journal ArticleDOI
Environmental risk factors in inflammatory bowel disease: a population-based case-control study in Asia-Pacific
Siew C. Ng,Whitney Tang,Rupert W. Leong,Minhu Chen,Yanna Ko,Corrie Studd,Ola Niewiadomski,Sally Bell,Michael A. Kamm,Michael A. Kamm,H.J. de Silva,Anuradhani Kasturiratne,Yasith Udara Senanayake,Choon Jin Ooi,Khoon Lin Ling,David E. Ong,Khean-Lee Goh,Ida Hilmi,Qin Ouyang,Yu-Fang Wang,Pin Jin Hu,Zhenhua Zhu,Zhirong Zeng,Kaichun Wu,Xin Wang,Bing Xia,Jin Li,Pises Pisespongsa,Sathaporn Manatsathit,Satimai Aniwan,Marcellus Simadibrata,Murdani Abdullah,Steve Tsang,Tai Chiu Wong,Aric J. Hui,Chung Mo Chow,Hon Ho Yu,Mo Fong Li,Ka Kei Ng,Jessica Y.L. Ching,Justin C.Y. Wu,Francis K.L. Chan,Joseph J.Y. Sung +42 more
TL;DR: This first population-based study of IBD risk factors in Asia-Pacific supports the importance of childhood immunological, hygiene and dietary factors in the development of IBF, suggesting that markers of altered intestinal microbiota may modulate risk of I BD later in life.
Journal Article
The emergence of inflammatory bowel disease in the Asian Pacific region
TL;DR: Investigation of inflammatory bowel disease in the Asian Pacific region offers the unprecedented opportunity to study the ‘early stages’ of the disease, and may provide new clues to its pathophysiology by identifying key environmental factors and distinct genetic make-ups.
Journal ArticleDOI
Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice.
Emiko Mizoguchi,Atsushi Mizoguchi,Hidetoshi Takedatsu,Elke Cario,Ype P. de Jong,Choon Jin Ooi,Ramnik J. Xavier,Cox Terhorst,Daniel K. Podolsky,Atul K. Bhan +9 more
TL;DR: In vitro studies showed that TNFR2 expression was up-regulated by a cooperative effect of key proinflammatory cytokines in CEC in both human ulcerative colitis and Crohn's disease, suggesting that TNfr2 may play an important role in colonic inflammation-associated alteration in the intestinal epithelium.
Journal ArticleDOI
Population Density and Risk of Inflammatory Bowel Disease: A Prospective Population-Based Study in 13 Countries or Regions in Asia-Pacific.
Siew C. Ng,Gilaad G. Kaplan,Whitney Tang,Rupa Banerjee,Bhargavi Adigopula,Fox E. Underwood,Divine Tanyingoh,Shu-Chen Wei,Wei-Chen Lin,Hung Hsin Lin,Jin Li,Sally Bell,O Niewiadomski,Michael A. Kamm,Zhirong Zeng,Minhu Chen,Pinjin Hu,David E. Ong,Choon Jin Ooi,Khoon Lin Ling,Yinglei Miao,Jiarong Miao,H. Janaka de Silva,Madunil A. Niriella,Satimai Aniwan,Julajak Limsrivilai,Pises Pisespongsa,Kaichun Wu,Hong Yang,Ka Kei Ng,Hon Ho Yu,Yu-Fang Wang,Qin Ouyang,Murdani Abdullah,Marcellus Simadibrata,Jeffri Gunawan,Ida Hilmi,Khean-Lee Goh,Qian Cao,Hong Sheng,Arlinking K. Ong-Go,Vui Heng Chong,Jessica Y.L. Ching,Justin C Y Wu,Francis K.L. Chan,Joseph J.Y. Sung +45 more
TL;DR: Wang et al. as discussed by the authors conducted a population-based study to assess the relationship between urbanization and incidence of inflammatory bowel disease (IBD) in the Asia-Pacific region.