C
Christian Pagnoux
Researcher at University of Toronto
Publications - 217
Citations - 9305
Christian Pagnoux is an academic researcher from University of Toronto. The author has contributed to research in topics: Vasculitis & Granulomatosis with polyangiitis. The author has an hindex of 42, co-authored 186 publications receiving 7186 citations. Previous affiliations of Christian Pagnoux include Mount Sinai Hospital, Toronto.
Papers
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Journal ArticleDOI
Rituximab versus Azathioprine for Maintenance in ANCA-Associated Vasculitis
Loïc Guillevin,Christian Pagnoux,Alexandre Karras,Chahéra Khouatra,Olivier Aumaître,Pascal Cohen,François Maurier,Olivier Decaux,Jacques Ninet,P. Gobert,Thomas Quemeneur,Claire Blanchard-Delaunay,Pascal Godmer,Xavier Puéchal,Pierre-Louis Carron,Pierre-Yves Hatron,Nicolas Limal,Mohamed Hamidou,Maize Ducret,Eric Daugas,Thomas Papo,Bernard Bonnotte,Alfred Mahr,Philippe Ravaud,Luc Mouthon +24 more
TL;DR: More patients with ANCA-associated vasculitides had sustained remission at month 28 with rituximab than with azathioprine, and the frequencies of severe adverse events were similar in the two groups.
Journal ArticleDOI
Antineutrophil Cytoplasmic Antibodies and the Churg–Strauss Syndrome
Régis Sablé-Fourtassou,Pascal Cohen,Alfred Mahr,Christian Pagnoux,Luc Mouthon,David Jayne,Daniel Engelbert Blockmans,Jean-François Cordier,Philippe Delaval,Xavier Puéchal,Dominique Lauque,Jean-François Viallard,Abdelkader Zoulim,Loïc Guillevin +13 more
TL;DR: The clinical characteristics of patients who recently received a diagnosis of the ChurgStrauss syndrome and who were included in prospective therapeutic trials organized by the French Vasculitis Study Group (FVSG) and the EUVAS were described to compare the characteristics of Patients with and without ANCA.
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Mycophenolate mofetil vs azathioprine for remission maintenance in antineutrophil cytoplasmic antibody-associated vasculitis: a randomized controlled trial.
Thomas F. Hiemstra,Michael Walsh,Alfred Mahr,Caroline O. S. Savage,Kirsten de Groot,Lorraine Harper,Thomas H. Hauser,Irmgard Neumann,Vladimir Tesar,Karl Martin Wissing,Christian Pagnoux,Wilhelm H. Schmitt,David Jayne +12 more
TL;DR: The International Mycophenolate Mofetil Protocol to Reduce Outbreaks of Vasculitides (IMPROVE) trial as mentioned in this paper was conducted at 42 centers in 11 European countries between 2002 and 2009 (42-month study).
Journal ArticleDOI
Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis
Michael Walsh,Peter A. Merkel,Chen-Au Peh,Wladimir Szpirt,Xavier Puéchal,Shouichi Fujimoto,Carmel M. Hawley,Nader Khalidi,Oliver Floßmann,Ron Wald,Louis Girard,Adeera Levin,Gina Gregorini,Lorraine Harper,William F. Clark,Christian Pagnoux,Ulrich Specks,Lucy Smyth,Vladimir Tesar,Toshiko Ito-Ihara,Toshiko Ito-Ihara,Janak de Zoysa,Wojciech Szczeklik,Luis Felipe Flores-Suárez,Simon Carette,L. Guillevin,Charles D. Pusey,Alina Casian,Biljana Brezina,Andrea Mazzetti,Carol A. McAlear,Elizabeth Broadhurst,Donna Reidlinger,Samir Mehta,Natalie Ives,David Jayne,Pexivas Investigators Pexivas Investigators +36 more
TL;DR: Among patients with severe ANCA-associated vasculitis, the use of plasma exchange did not reduce the incidence of death or ESKD, and a reduced-dose regimen of glucocorticoids was noninferior to a standard- dose regimen with respect to death orESKD.
Journal ArticleDOI
Eosinophilic granulomatosis with polyangiitis (Churg-Strauss) (EGPA) Consensus Task Force recommendations for evaluation and management.
Matthieu Groh,Christian Pagnoux,Chiara Baldini,Elisabeth H. Bel,Paolo Bottero,Vincent Cottin,Klaus Dalhoff,Bertrand Dunogué,Wolfgang L. Gross,Julia U Holle,Marc Humbert,David Jayne,J. Charles Jennette,Romain Lazor,Alfred Mahr,Peter A. Merkel,Luc Mouthon,Renato Alberto Sinico,Ulrich Specks,Augusto Vaglio,Michael E. Wechsler,Jean-François Cordier,Loïc Guillevin +22 more
TL;DR: These recommendations aim to give physicians tools for effective and individual management of EGPA patients, and to provide guidance for further targeted research.