Renato Alberto Sinico

TL;DR: Plasma exchange increased the rate of renal recovery in ANCA-associated systemic vasculitis that presented with renal failure when compared with intravenous methylprednisolone, and survival and severe adverse event rates were similar in both groups.

TL;DR: The data from the ELNT indicate that in European SLE patients with proliferative lupus nephritis, a remission-inducing regimen of low-dose IV CYC (cumulative dose 3 gm) followed by AZA achieves clinical results comparable to those obtained with a high-dose regimen.

TL;DR: In this article, the authors compared pulse cyclophosphamide with daily oral cyclophotonitrile (OC) for the treatment of generalized ANCA-associated vasculitis with renal involvement but not immediately life-threatening disease.

TL;DR: The prevalence and antigen specificity of ANCAs in a large cohort of patients with Churg-Strauss syndrome was examined and the relationship between ANCA positivity and clinicopathologic features was evaluated.

TL;DR: Recommendations for the assessment and interpretation of ANA and associated antibodies were formulated and the roles of IIFA as a reference method, and the importance of defining nuclear and cytoplasmic staining were emphasised, while the need to incorporate alternative automated methods was acknowledged.