C
Christian Schmidt-Lauber
Researcher at University of Massachusetts Medical School
Publications - 16
Citations - 603
Christian Schmidt-Lauber is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 5, co-authored 6 publications receiving 362 citations. Previous affiliations of Christian Schmidt-Lauber include University of Münster.
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Journal ArticleDOI
Cutting Edge: FAS (CD95) Mediates Noncanonical IL-1β and IL-18 Maturation via Caspase-8 in an RIP3-Independent Manner
Lukas Bossaller,Ping-I Chiang,Christian Schmidt-Lauber,Sandhya Ganesan,William J. Kaiser,Vijay A. K. Rathinam,Edward S. Mocarski,Deepa Subramanian,Douglas R. Green,Neal S. Silverman,Katherine A. Fitzgerald,Ann Marshak-Rothstein,Ann Marshak-Rothstein,Eicke Latz,Eicke Latz,Eicke Latz +15 more
TL;DR: It is demonstrated that macrophages exposed to TLR ligands upregulate Fas, which renders them responsive to receptor engagement by Fas ligand, which controls a novel noncanonical IL-1β activation pathway in myeloid cells, which could play an essential role in inflammatory processes, tumor surveillance, and control of infectious diseases.
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Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme
Elina Petersen,Alina Goßling,Gerhard Adam,Martin Aepfelbacher,Christian-Alexander Behrendt,Ersin Cavus,B. Cheng,Nicole Fischer,Jürgen Gallinat,Simone Kühn,Christian Gerloff,Uwe Koch-Gromus,Martin Härter,Uta Hanning,Tobias B. Huber,Stefan Kluge,Johannes Knobloch,Piotr Kuta,Christian Schmidt-Lauber,Marc Lütgehetmann,Christina Magnussen,Carola Mayer,Kai Muellerleile,Julia Münch,Felix Nägele,Marvin Petersen,Thomas Renné,Katharina A. Riedl,David Leander Rimmele,I Schäfer,Holger Schulz,Enver Tahir,Benjamin Waschki,Jan Per Wenzel,Tanja Zeller,Andreas Ziegler,Götz Thomalla,Raphael Twerenbold,Stefan Blankenberg +38 more
TL;DR: Subjects who apparently recovered from mild to moderate SARS-CoV-2 infection show signs of subclinical multi-organ affection related to pulmonary, cardiac, thrombotic, and renal function without signs of structural brain damage, neurocognitive, or quality-of-life impairment.
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Nephrogenic systemic fibrosis: A systemic fibrosing disease resulting from gadolinium exposure
TL;DR: The history, clinical manifestations, epidemiology, histopathology and pathophysiology ofephrogenic systemic fibrosis are reviewed.
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Molecular consequences of SARS-CoV-2 liver tropism
Nicola Wanner,Geoffroy Andrieux,Pau Badia-i-Mompel,Carolin Edler,Susanne Pfefferle,Maja T. Lindenmeyer,Christian Schmidt-Lauber,Jan Czogalla,Milagros N. Wong,Yusuke Okabayashi,Fabian Braun,Marc Lütgehetmann,Elisabeth Meister,Shun Lu,Maria de las Mercedes Noriega,Thomas Günther,Adam Grundhoff,Nicole Fischer,Hanna Bräuninger,Diana Lindner,Dirk Westermann,Fabian Haas,Kevin Roedl,Stefan Kluge,Marylyn M. Addo,Samuel Huber,Ansgar W. Lohse,Jochen Reiser,Benjamin Ondruschka,Jan-Peter Sperhake,Julio Saez-Rodriguez,Melanie Boerries,Salim S. Hayek,Martin Aepfelbacher,Pietro Scaturro,Victor G. Puelles,Tobias B. Huber +36 more
TL;DR: In this article , the authors provide clinical, histopathological, molecular and bioinformatic evidence for the hepatic tropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) showing tropism towards several organs, including the heart and kidney.
Journal ArticleDOI
Gadolinium-based compounds induce NLRP3-dependent IL-1β production and peritoneal inflammation
Christian Schmidt-Lauber,Lukas Bossaller,Hani H. Abujudeh,Gregory I. Vladimer,Anette Christ,Katherine A. Fitzgerald,Eicke Latz,Ellen M. Gravallese,Ann Marshak-Rothstein,Jonathan Kay +9 more
TL;DR: It is suggested that Gd released from GBCAs triggers a NLRP3 inflammasome-dependent inflammatory response that leads to fibrosis in an appropriate clinical setting.