J
Jan Czogalla
Researcher at University of Zurich
Publications - 13
Citations - 338
Jan Czogalla is an academic researcher from University of Zurich. The author has contributed to research in topics: Medicine & Kidney. The author has an hindex of 5, co-authored 6 publications receiving 179 citations. Previous affiliations of Jan Czogalla include University of Hamburg.
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Journal ArticleDOI
Extracellular K+ rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl- -dependent and independent mechanisms.
David Penton,Jan Czogalla,Agnieszka Wengi,Nina Himmerkus,Dominique Loffing-Cueni,Monique Carrel,Renuga Devi Rajaram,Renuga Devi Rajaram,Olivier Staub,Olivier Staub,Markus Bleich,Frank Schweda,Johannes Loffing +12 more
TL;DR: In this paper, it was shown that a high dietary potassium intake causes a rapid dephosphorylation, and hence inactivation, of the thiazide-sensitive NaCl cotransporter (NCC) in the renal distal convoluted tubule (DCT).
Journal ArticleDOI
Molecular consequences of SARS-CoV-2 liver tropism
Nicola Wanner,Geoffroy Andrieux,Pau Badia-i-Mompel,Carolin Edler,Susanne Pfefferle,Maja T. Lindenmeyer,Christian Schmidt-Lauber,Jan Czogalla,Milagros N. Wong,Yusuke Okabayashi,Fabian Braun,Marc Lütgehetmann,Elisabeth Meister,Shun Lu,Maria de las Mercedes Noriega,Thomas Günther,Adam Grundhoff,Nicole Fischer,Hanna Bräuninger,Diana Lindner,Dirk Westermann,Fabian Haas,Kevin Roedl,Stefan Kluge,Marylyn M. Addo,Samuel Huber,Ansgar W. Lohse,Jochen Reiser,Benjamin Ondruschka,Jan-Peter Sperhake,Julio Saez-Rodriguez,Melanie Boerries,Salim S. Hayek,Martin Aepfelbacher,Pietro Scaturro,Victor G. Puelles,Tobias B. Huber +36 more
TL;DR: In this article , the authors provide clinical, histopathological, molecular and bioinformatic evidence for the hepatic tropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) showing tropism towards several organs, including the heart and kidney.
Journal ArticleDOI
Dietary potassium and the renal control of salt balance and blood pressure
TL;DR: Findings suggesting that an aldosterone-independent downregulation of the thiazide-sensitive NaCl cotransporter significantly contributes to the natriuretic and antihypertensive effect of a K+-rich diet are given.
Journal ArticleDOI
The mineralocorticoid receptor (MR) regulates ENaC but not NCC in mice with random MR deletion
TL;DR: It is shown that MR is crucial for ENaC and Na+-K+-ATPase regulation in the CS, but is dispensable for NCC and Na-K-atPaseregulation in the DCT.
Journal ArticleDOI
The Mouse Isolated Perfused Kidney Technique
TL;DR: The perfusate and the surgical technique needed for the ex vivo perfusion of mouse kidneys are described and data is presented showing the viability of the kidney's preparation.